Protein Alignment Cdc42 and RHOBTB1

DIOPT Version :10

• Sequence 1: NP_523414.1
• Gene: Cdc42 / 32981
• FlyBaseID: FBgn0010341
• Length: 191
• Species: Drosophila melanogaster
• Sequence 2: NP_055651.1
• Gene: RHOBTB1 / 9886
• HGNCID: 18738
• Length: 696
• Species: Homo sapiens
• Alignment Length: 202
• Identity: 80/202 - (39%)
• Similarity: 117/202 - (57%)
• Gaps: 30/202 - (14%)

  Fly     1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV--------MIGGE 49
            ::|||||||||.|||||.|:.:...|...::|      ||||:  |.|.|..        ::...
Human    12 VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDEV 76

  Fly    50 PYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVG 114
            ..:|.|:||.|  |:.:.|..:|.::||.::|||:.:|:|..:||..|.|||.|.|.:||.:|||
Human    77 SVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPRTPVILVG 139

  Fly   115 TQIDLRDENSTLEKLAKNKQ---KPITM------EQGEKLAKELKAVKYVECSALTQKGLKNVFD 170
            .|:|||  .:.||.:.:.::   :||..      |:|.::|||| .:.|.|.|...|.|:|:|||
Human   140 CQLDLR--YADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GLPYYETSVFDQFGIKDVFD 201

  Fly   171 EAILAAL 177
            .||.|||
Human   202 NAIRAAL 208

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc42	NP_523414.1	Cdc42	3..177	CDD:206664	78/198 (39%)
RHOBTB1	NP_055651.1	Rho-like	1..210		80/202 (40%)
		RhoBTB	13..207	CDD:133275	77/198 (39%)
		BTB1_POZ_RHOBTB1	248..460	CDD:349664
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..348
		BTB2_POZ_RHOBTB1	465..590	CDD:349667
		BACK_RHOBTB1	593..692	CDD:350605