DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cdc42 and RHO5

DIOPT Version :9

Sequence 1:NP_001245762.1 Gene:Cdc42 / 32981 FlyBaseID:FBgn0010341 Length:191 Species:Drosophila melanogaster
Sequence 2:NP_014219.1 Gene:RHO5 / 855541 SGDID:S000005124 Length:331 Species:Saccharomyces cerevisiae


Alignment Length:227 Identity:104/227 - (45%)
Similarity:140/227 - (61%) Gaps:42/227 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMI------------------- 46
            |::||||::||||||||.||||||||.||::|||||||||:.|:.|                   
Yeast     1 MRSIKCVIIGDGAVGKTSLLISYTTNSFPTDYVPTVFDNYSTTIAIPNGTASSPLELDNGNDKRG 65

  Fly    47 -----GGEP------YTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPE 100
                 ...|      |.:.|:||||||||||||||.|||||:||:||||...:||.||.|||:||
Yeast    66 SLSSASSSPSTDRKLYKINLWDTAGQEDYDRLRPLCYPQTDIFLICFSVSEHASFANVTEKWLPE 130

  Fly   101 I--THHCQ---------KTPFLLVGTQIDLRDENSTLEKLAKNKQKPITMEQGEKLAKELKAVKY 154
            :  |.:.:         |.|.|||||:.||||:.:|.:||.:.....::.|:.::|.:....:.|
Yeast   131 LKQTSNIEGTSLYTKLGKYPILLVGTKSDLRDDPATQKKLQEANSDYVSQEEIDELVQRCGFMGY 195

  Fly   155 VECSALTQKGLKNVFDEAILAAL-EPPEPTKK 185
            .||||.||.|::.||::|:..|: ||..|.:|
Yeast   196 TECSAATQAGVREVFEQAVRYAIYEPESPNQK 227

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cdc42NP_001245762.1 Cdc42 3..177 CDD:206664 98/214 (46%)
RHO 6..179 CDD:197554 97/214 (45%)
RHO5NP_014219.1 RHO 6..220 CDD:197554 97/213 (46%)
PBP1 <161..>316 CDD:227507 23/67 (34%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG0393
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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