DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdc42 and Rhobtb1

DIOPT Version :9

Sequence 1:	NP_001245762.1	Gene:	Cdc42 / 32981	FlyBaseID:	FBgn0010341	Length:	191	Species:	Drosophila melanogaster
Sequence 2:	NP_001074816.1	Gene:	Rhobtb1 / 69288	MGIID:	1916538	Length:	695	Species:	Mus musculus

Alignment Length:	202	Identity:	79/202 - (39%)
Similarity:	116/202 - (57%)	Gaps:	30/202 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV--------MIGGE 49
            ::|||||||||.|||||.|:.:...|...::|      ||||:  |.|.|..        ::...
Mouse    12 VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDEV 76

  Fly    50 PYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVG 114
            ..:|.|:||.|  |:.:.|..:|.::||.::|||:.:|:|..:||..|..||.|.|.:||.:|||
Mouse    77 SISLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKTMWYQEIKHFCPRTPVVLVG 139

  Fly   115 TQIDLRDENSTLEKLAKNKQ---KPITM------EQGEKLAKELKAVKYVECSALTQKGLKNVFD 170
            .|:|||  .:.||.:.:.::   :||..      |:|.::|||| .:.|.|.|...|.|:|:|||
Mouse   140 CQLDLR--YADLEAVNRARRPLARPIKRGDILPPEKGREVAKEL-GIPYYETSVFDQFGIKDVFD 201

  Fly   171 EAILAAL 177
            .||.|||
Mouse   202 NAIRAAL 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdc42	NP_001245762.1	Cdc42	3..177	CDD:206664	77/198 (39%)
Cdc42	NP_001245762.1	RHO	6..179	CDD:197554	76/197 (39%)
Rhobtb1	NP_001074816.1	Rho-like	1..210		79/202 (39%)
		RhoBTB	13..207	CDD:133275	76/198 (38%)
		BTB_POZ	248..459	CDD:365784
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	325..351
		BTB_POZ	464..589	CDD:365784
		BACK_RHOBTB1	592..691	CDD:350605
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810