Protein Alignment Cdc42 and RHOF

DIOPT Version :9

• Sequence 1: NP_001245762.1
• Gene: Cdc42 / 32981
• FlyBaseID: FBgn0010341
• Length: 191
• Species: Drosophila melanogaster
• Sequence 2: NP_061907.2
• Gene: RHOF / 54509
• HGNCID: 15703
• Length: 211
• Species: Homo sapiens
• Alignment Length: 192
• Identity: 87/192 - (45%)
• Similarity: 127/192 - (66%)
• Gaps: 4/192 - (2%)

  Fly     4 IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLR 68
            :|.|:||||..|||.||:.|:...||..|.|:||:.|..:|.:|.:..||.|:||||||||||||
Human    20 LKIVIVGDGGCGKTSLLMVYSQGSFPEHYAPSVFEKYTASVTVGSKEVTLNLYDTAGQEDYDRLR 84

  Fly    69 PLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVGTQIDLRDENSTLEKLAKNK 133
            ||||..|.:.|:|:.|::|:|::||..||.||:||.|:..|.:|:|.:.|||.:...|.||...:
Human    85 PLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPMVLIGCKTDLRKDKEQLRKLRAAQ 149

  Fly   134 QKPITMEQGEKLAKELKAVKYVECSALTQKGLKNVFDEA---ILAALEPPEPTKKRK-CKFL 191
            .:|||..||....::::|..|:||||..::.:::||.||   .|:||:..:..|||: |..|
Human   150 LEPITYMQGLSACEQIRAALYLECSAKFRENVEDVFREAAKVALSALKKAQRQKKRRLCLLL 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc42	NP_001245762.1	Cdc42	3..177	CDD:206664	80/175 (46%)
		RHO	6..179	CDD:197554	81/175 (46%)
RHOF	NP_061907.2	Rho4_like	17..211	CDD:206704	86/190 (45%)
		RHO	22..195	CDD:197554	79/172 (46%)
		Effector region. /evidence=ECO:0000255	48..56		4/7 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1091615at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820