Protein Alignment Cdc42 and RHOG

DIOPT Version :10

• Sequence 1: NP_523414.1
• Gene: Cdc42 / 32981
• FlyBaseID: FBgn0010341
• Length: 191
• Species: Drosophila melanogaster
• Sequence 2: NP_001656.2
• Gene: RHOG / 391
• HGNCID: 672
• Length: 191
• Species: Homo sapiens
• Alignment Length: 191
• Identity: 115/191 - (60%)
• Similarity: 141/191 - (73%)
• Gaps: 0/191 - (0%)

  Fly     1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYD 65
            ||:||||||||||||||||||.||||.||.||:|||||||:....:.|....|.|:||||||:||
Human     1 MQSIKCVVVGDGAVGKTCLLICYTTNAFPKEYIPTVFDNYSAQSAVDGRTVNLNLWDTAGQEEYD 65

  Fly    66 RLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVGTQIDLRDENSTLEKLA 130
            |||.||||||:||::|||:.||.|:|||:.||.||:.|||...|.|||||:.|||.:..||.:|.
Human    66 RLRTLSYPQTNVFVICFSIASPPSYENVRHKWHPEVCHHCPDVPILLVGTKKDLRAQPDTLRRLK 130

  Fly   131 KNKQKPITMEQGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALEPPEPTKKRKCKFL 191
            :..|.|||.:||:.|||::.||:|:|||||.|.|:|.||.||:.|.|.|....:.|.|..|
Human   131 EQGQAPITPQQGQALAKQIHAVRYLECSALQQDGVKEVFAEAVRAVLNPTPIKRGRSCILL 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc42	NP_523414.1	Cdc42	3..177	CDD:206664	108/173 (62%)
RHOG	NP_001656.2	RhoG	1..191	CDD:133277	114/189 (60%)
		Effector region. /evidence=ECO:0000255	32..40		6/7 (86%)