Protein Alignment Cdc42 and Rhof

DIOPT Version :10

• Sequence 1: NP_523414.1
• Gene: Cdc42 / 32981
• FlyBaseID: FBgn0010341
• Length: 191
• Species: Drosophila melanogaster
• Sequence 2: NP_780301.1
• Gene: Rhof / 23912
• MGIID: 1345629
• Length: 211
• Species: Mus musculus
• Alignment Length: 192
• Identity: 86/192 - (44%)
• Similarity: 124/192 - (64%)
• Gaps: 4/192 - (2%)

  Fly     4 IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLR 68
            :|.|:||||..|||.||:.|....||..|.|:||:.|..:|.:|.:..||.|:||||||||||||
Mouse    20 LKIVIVGDGGCGKTSLLMVYCQGSFPEHYAPSVFEKYTASVTVGNKEVTLNLYDTAGQEDYDRLR 84

  Fly    69 PLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVGTQIDLRDENSTLEKLAKNK 133
            ||||..|.:.|:|:.|::|:|::||..||.||:||.|:..|.:|:|.:.|||.:...|.||...:
Mouse    85 PLSYQNTHLVLICYDVMNPTSYDNVLIKWFPEVTHFCRGIPTVLIGCKTDLRKDKEQLRKLRAAQ 149

  Fly   134 QKPITMEQGEKLAKELKAVKYVECSALTQKGLKNVFDEA---ILAALEPPEPTKK-RKCKFL 191
            .:|||..||....::::...|:||||..::.:::||.||   .|:||:..:..|| |.|..|
Mouse   150 LEPITYTQGLNACEQMRGALYLECSAKFRENVEDVFREAAKVALSALKKAQRQKKHRICLLL 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cdc42	NP_523414.1	Cdc42	3..177	CDD:206664	79/175 (45%)
Rhof	NP_780301.1	Rho4_like	17..211	CDD:206704	85/190 (45%)
		Effector region. /evidence=ECO:0000255	48..56		4/7 (57%)