DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdc42 and mig-2

DIOPT Version :9

Sequence 1:	NP_001245762.1	Gene:	Cdc42 / 32981	FlyBaseID:	FBgn0010341	Length:	191	Species:	Drosophila melanogaster
Sequence 2:	NP_509931.1	Gene:	mig-2 / 181344	WormBaseID:	WBGene00003239	Length:	195	Species:	Caenorhabditis elegans

Alignment Length:	188	Identity:	114/188 - (60%)
Similarity:	143/188 - (76%)	Gaps:	0/188 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLR 68
            |||||||||.|||||:||||||:.||.:|||||||||:..:.:.|....|||:||||||||||||
Worm     8 IKCVVVGDGTVGKTCMLISYTTDSFPVQYVPTVFDNYSAQMSLDGNVVNLGLWDTAGQEDYDRLR 72

  Fly    69 PLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVGTQIDLRDENSTLEKLAKNK 133
            ||||||||||::|||||||.||:||..||:|||..||...|.:||||::|||||...:..|....
Worm    73 PLSYPQTDVFILCFSVVSPVSFDNVASKWIPEIRQHCPDAPVILVGTKLDLRDEAEPMRALQAEG 137

  Fly   134 QKPITMEQGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALEPPEPTKKRKCKFL 191
            :.||:..||.|:|:::|||||:|||||||:||..||::|:.:.|.|....||:.|..:
Worm   138 KSPISKTQGMKMAQKIKAVKYLECSALTQQGLTQVFEDAVRSILHPKPQKKKKSCNIM 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdc42	NP_001245762.1	Cdc42	3..177	CDD:206664	109/172 (63%)
Cdc42	NP_001245762.1	RHO	6..179	CDD:197554	108/172 (63%)
mig-2	NP_509931.1	Rho	8..178	CDD:206641	109/169 (64%)
mig-2	NP_509931.1	RHO	10..183	CDD:197554	108/172 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1091615at2759
OrthoFinder	1	1.000	-	-		FOG0000070
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X103
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820