DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdc42 and Rnd2

DIOPT Version :9

Sequence 1:	NP_001245762.1	Gene:	Cdc42 / 32981	FlyBaseID:	FBgn0010341	Length:	191	Species:	Drosophila melanogaster
Sequence 2:	NP_033838.1	Gene:	Rnd2 / 11858	MGIID:	1338755	Length:	227	Species:	Mus musculus

Alignment Length:	174	Identity:	71/174 - (40%)
Similarity:	109/174 - (62%)	Gaps:	1/174 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 KCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRP 69
            |.|||||...|||.||..:..:.:|..||||||:||..:..|......|.::||:|...||.:||
Mouse     9 KIVVVGDAECGKTALLQVFAKDAYPGSYVPTVFENYTASFEIDKRRIELNMWDTSGSSYYDNVRP 73

  Fly    70 LSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVGTQIDLRDENSTLEKLAKNKQ 134
            |:||.:|..|:||.:..|.:.::|.:||..|....|.....:|||.::|:|.:.:||.:|:|.:.
Mouse    74 LAYPDSDAVLICFDISRPETLDSVLKKWQGETQEFCPNAKVVLVGCKLDMRTDLATLRELSKQRL 138

  Fly   135 KPITMEQGEKLAKELKAVKYVECSA-LTQKGLKNVFDEAILAAL 177
            .|:|.|||..|||::.||.|||||: .:::.:::||..|.:|:|
Mouse   139 IPVTHEQGTVLAKQVGAVSYVECSSRSSERSVRDVFHVATVASL 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdc42	NP_001245762.1	Cdc42	3..177	CDD:206664	70/172 (41%)
Cdc42	NP_001245762.1	RHO	6..179	CDD:197554	70/173 (40%)
Rnd2	NP_033838.1	Rnd2_Rho7	7..227	CDD:206736	71/174 (41%)
		Effector region. /evidence=ECO:0000255	36..44		6/7 (86%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	186..227
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900