DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdc42 and Rhoq

DIOPT Version :9

Sequence 1:	NP_001245762.1	Gene:	Cdc42 / 32981	FlyBaseID:	FBgn0010341	Length:	191	Species:	Drosophila melanogaster
Sequence 2:	NP_663466.2	Gene:	Rhoq / 104215	MGIID:	1931553	Length:	205	Species:	Mus musculus

Alignment Length:	184	Identity:	127/184 - (69%)
Similarity:	154/184 - (83%)	Gaps:	0/184 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLR 68
            :||||||||||||||||:||..:.||.||||||||:|||:|.:||:.|.|||:||||||||||||
Mouse    10 LKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVSVTVGGKQYLLGLYDTAGQEDYDRLR 74

  Fly    69 PLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVGTQIDLRDENSTLEKLAKNK 133
            |||||.|||||:|||||:|:||:||||:||||:..:....||||:||||||||:..||.:|...|
Mouse    75 PLSYPMTDVFLICFSVVNPASFQNVKEEWVPELKEYAPNVPFLLIGTQIDLRDDPKTLARLNDMK 139

  Fly   134 QKPITMEQGEKLAKELKAVKYVECSALTQKGLKNVFDEAILAALEPPEPTKKRK 187
            :||:.:|||:|||||:.|..|||||||||||||.||||||:|.|.|.:.|.|::
Mouse   140 EKPVCVEQGQKLAKEIGACCYVECSALTQKGLKTVFDEAIIAILTPKKHTVKKR 193

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdc42	NP_001245762.1	Cdc42	3..177	CDD:206664	123/172 (72%)
Cdc42	NP_001245762.1	RHO	6..179	CDD:197554	123/172 (72%)
Rhoq	NP_663466.2	Tc10	10..183	CDD:206707	123/172 (72%)
Rhoq	NP_663466.2	Effector region. /evidence=ECO:0000250	38..46		7/7 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1091615at2759
OrthoFinder	1	1.000	-	-		FOG0000070
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X103
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820