DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdc42 and rhobtb1

DIOPT Version :9

Sequence 1:	NP_001245762.1	Gene:	Cdc42 / 32981	FlyBaseID:	FBgn0010341	Length:	191	Species:	Drosophila melanogaster
Sequence 2:	XP_003199615.1	Gene:	rhobtb1 / 100537290	ZFINID:	ZDB-GENE-130530-871	Length:	687	Species:	Danio rerio

Alignment Length:	202	Identity:	78/202 - (38%)
Similarity:	115/202 - (56%)	Gaps:	30/202 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV--------MIGGE 49
            ::|||||||||.|||||.|:.:...|...::|      ||||:  |.|.|..        ::...
Zfish     8 VETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDV 72

  Fly    50 PYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVG 114
            ..:|.|:||.|  |:.:.|..:|.::||.::|||:.:|:|..:||..|..||.|.|.:||.:|||
Zfish    73 SVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYLEIKHFCPRTPVILVG 135

  Fly   115 TQIDLRDENSTLEKLAKNKQ------KP---ITMEQGEKLAKELKAVKYVECSALTQKGLKNVFD 170
            .|:|||  .:.||.:.:.::      ||   :..|.|.::|||| .:.|.|.|...|.|:|::||
Zfish   136 CQLDLR--YADLEAVNRARRPLSRPIKPGDILPPESGREVAKEL-GIPYYETSVFDQFGIKDIFD 197

  Fly   171 EAILAAL 177
            .||.|||
Zfish   198 NAIRAAL 204

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdc42	NP_001245762.1	Cdc42	3..177	CDD:206664	76/198 (38%)
Cdc42	NP_001245762.1	RHO	6..179	CDD:197554	75/197 (38%)
rhobtb1	XP_003199615.1	RhoBTB	9..203	CDD:133275	75/198 (38%)
		BTB	355..446	CDD:333434
		BTB	477..569	CDD:197585
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0393
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810