DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cdc42 and rhobtb2

DIOPT Version :9

Sequence 1:	NP_001245762.1	Gene:	Cdc42 / 32981	FlyBaseID:	FBgn0010341	Length:	191	Species:	Drosophila melanogaster
Sequence 2:	XP_004912583.1	Gene:	rhobtb2 / 100144291	XenbaseID:	XB-GENE-964295	Length:	718	Species:	Xenopus tropicalis

Alignment Length:	200	Identity:	77/200 - (38%)
Similarity:	114/200 - (56%)	Gaps:	26/200 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEY------VPTVF--DNYAVTV--------MIGGE 49
            ::|||||||||.|||||.|:.:...|...::|      ||||:  |.|.|..        ::...
Frog    45 VETIKCVVVGDNAVGKTRLICARACNATLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDV 109

  Fly    50 PYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCQKTPFLLVG 114
            ..:|.|:||.|  |:.:.|..:|.::||.::|||:.:|:|.::|:..|.|||.|.|.:.|.:|||
Frog   110 SVSLRLWDTFG--DHHKDRRFAYGRSDVVVLCFSIANPNSLQHVQTMWYPEIKHFCPRAPVILVG 172

  Fly   115 TQIDLR-----DENSTLEKLAK--NKQKPITMEQGEKLAKELKAVKYVECSALTQKGLKNVFDEA 172
            .|:|||     ..|.....||:  ..|:.:..|:|.::|||| .:.|.|.|.:.|.|:|.|||.|
Frog   173 CQLDLRYADLEAVNRARRPLARPIRPQEILPPEKGREVAKEL-GIPYYETSVVAQCGIKEVFDNA 236

  Fly   173 ILAAL 177
            |.:||
Frog   237 IRSAL 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cdc42	NP_001245762.1	Cdc42	3..177	CDD:206664	75/196 (38%)
Cdc42	NP_001245762.1	RHO	6..179	CDD:197554	73/194 (38%)
rhobtb2	XP_004912583.1	RhoBTB	46..240	CDD:133275	75/196 (38%)
		BTB_POZ	283..470	CDD:365784
		BTB_POZ	475..598	CDD:365784
		BACK	603..699	CDD:391941
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910