DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Mer and ccdc120a

DIOPT Version :9

Sequence 1:	NP_001285458.1	Gene:	Mer / 32979	FlyBaseID:	FBgn0086384	Length:	635	Species:	Drosophila melanogaster
Sequence 2:	XP_001921819.3	Gene:	ccdc120a / 799619	ZFINID:	ZDB-GENE-081104-59	Length:	601	Species:	Danio rerio

Alignment Length:	301	Identity:	60/301 - (19%)
Similarity:	100/301 - (33%)	Gaps:	96/301 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   340 REKAEH--ERYELEKSMEHLQNEMRMANDALRRSEETKELYFEKSRV-----NEEQMQLTECKAN 397
            :::||.  |..|..:|::.|.|         .|..|.|.|..:::.:     :|..::..| ||.
Zfish    20 KQRAERMVELQERRRSLQSLLN---------TRLAELKRLCLQEAELTGEVPHEYPLESGE-KAP 74

  Fly   398 HFKTEMDRLRERQMKIEREKHDLEKKIRDADFYVHQLTVENDKREAETEKLRKELICAKMAEREA 462
            |.:      |...:.....||:                .:|::.:....|.:|.|....:...
Zfish    75 HVR------RRAGLSRSSSKHN----------------TKNEEEDGSQRKTKKTLFSGALRRH-- 115

  Fly   463 TARLLEFLNSGRKSSTDSLLTASSVSHAANTASSMAAISTPSLITSSSTND---LETAGGAELTT 524
                    ....:....|..|.....|..||..|          .||||:|   .:|...::..:
Zfish   116 --------TDAEQHPQHSKRTVHRGCHTENTVKS----------ESSSTSDSTIQDTEDVSDSLS 162

  Fly   525 HSSHYLVQGDNSSGISDDFEPKEFILTDNEMEQITNEMERNHLDYLRNSKQVQSQLQTLRSEIAP 589
            .|...||.|...:.||....|.|          |..||:..     |||         :.|..:|
Zfish   163 PSRLKLVSGSPDNRISRKLSPVE----------IYYEMKTR-----RNS---------VASSASP 203

  Fly   590 -HKIEENQSNLDILSEAQIKAGENKYSTLKKLKSGSTKARV 629
             |.:..:.|||:         |.:..:|....::|.|.|.:
Zfish   204 SHSLPRSVSNLE---------GRSVPATPLLSRNGITGAHI 235

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mer	NP_001285458.1	B41	14..216	CDD:214604
		FERM_C_ERM	210..306	CDD:270015
		ERM	341..635	CDD:395622	60/300 (20%)
ccdc120a	XP_001921819.3	DUF3338	20..>81	CDD:288652	17/76 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3529
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900