Protein Alignment Mer and ezr

DIOPT Version :9

• Sequence 1: NP_001285458.1
• Gene: Mer / 32979
• FlyBaseID: FBgn0086384
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_001025629.1
• Gene: ezr / 595017
• XenbaseID: XB-GENE-484766
• Length: 582
• Species: Xenopus tropicalis
• Alignment Length: 638
• Identity: 257/638 - (40%)
• Similarity: 378/638 - (59%)
• Gaps: 70/638 - (10%)

  Fly    10 RSLSVRVSTFDSELEFKLEPRASGQDLFDLVCRTIGLRESWYFGLQYVDTRSNVSWLKMEKRVRD 74
            :.::|||:|.|:||||.::|..:|:.|||.|.:|:||||.||||||.:|.:..::|||::|:|..
 Frog     3 KPVNVRVTTMDAELEFAIQPSTTGKQLFDQVIKTVGLREVWYFGLQCIDNKGYLTWLKLDKKVSA 67

  Fly    75 QRVELHASNNVYVFSFYAKFFPENVSEELIQEITQHLFFLQVKQSILSMDIYCRPEASVLLASYA 139
            |.|:   ..|...|.|.|||:||:|||||||||||.|||||||::|||.::||.||.:|||||||
 Frog    68 QEVK---KENPLQFKFRAKFYPEDVSEELIQEITQKLFFLQVKEAILSDEVYCPPETAVLLASYA 129

  Fly   140 VHVQYGPYDYETYKDGMLAGGELLPKGVTDQYQMTPEMWEERIKTWYMDHEPMTRDEVEMEYLKI 204
            |..::|.|..||.|.|.|....|||:.|.||:.::.:.|||||:.|:.:|..|.:::..:|||||
 Frog   130 VQAKFGDYSKETIKSGYLTSERLLPQRVLDQHNLSRDQWEERIEVWHSEHRGMLKEDAMLEYLKI 194

  Fly   205 AQDLDMYGVNYFPITNKNKTKLWLGVTSVGLNIYDERDKLTPKTTFQWNEIRHVSFDDKKFTIRL 269
            ||||:|||:|||.|.||..:.|||||.::|||||:..||||||..|.|:|||::||:||||.|:.
 Frog   195 AQDLEMYGINYFEIKNKKGSDLWLGVDALGLNIYEHNDKLTPKIGFPWSEIRNISFNDKKFVIKP 259

  Fly   270 VDAKVSNFIFYSQDLHINKMILDLCKGNHDLYMRRRKPDTMEIQQMKAQAKEEKQRRQIERKKFI 334
            :|.|..:|:||:..|.|||.||.||.|||:||||||||||:|:|||||||||||.::|:||::..
 Frog   260 IDKKAPDFVFYAPRLRINKRILQLCMGNHELYMRRRKPDTIEVQQMKAQAKEEKLQKQLERQQLE 324

  Fly   335 REKKLREKAEHERYELEKSMEHLQNEMRMANDALRRSEETKELYFEKSRVNEEQMQLTECKANHF 399
            :|||.||..|.||.::.|..|.|...:....:..:|:|.......::::..||:.:..:.:|
 Frog   325 QEKKKREAIEREREQMIKEKEELMFRLHEYEEQSKRAERELSEQIQRAKELEEERRRAQYEA--- 386

  Fly   400 KTEMDRLRERQMKIEREKHDLEKKIRDADFYVHQLTVENDKREAETEKLRKELICAKMAEREATA 464
                :||...::...|.|.:||                   |:|..:...:|.:.::::|..|..
 Frog   387 ----ERLEAERISALRAKEELE-------------------RQAIAQTKSQEQLASELSEYTARI 428

  Fly   465 RLL------------EFLNSGRKSSTDSLLTASSVSHAANTASSMAAISTPSLITSSSTNDLETA 517
            .||            |:....:::.||.|.|...:.....|...    ..|.:......:  |..
 Frog   429 SLLEEARRVKEDEASEWQMRAQEAQTDLLRTREELHMVMTTPPP----PPPPVYEPYRVH--EPD 487

  Fly   518 GGAELTTHSSHYLVQGDNSSGISDDFEPKEFILTDNEMEQITNEMERNHLDYLRNSKQVQSQLQT 582
            .|.|.|::|:..         .|.||      |.||:|:....|.|:|        ::||.||..
 Frog   488 DGLEHTSYSAEL---------SSVDF------LEDNKMQTRMTEAEKN--------ERVQRQLMA 529

  Fly   583 LRSEIAPHKIEENQSNLDILSEAQIKAGENKYSTLKKLKSGSTKARVAFFEEL 635
            |.||::..:.|..:::.|||....:|:|.:||.||::::.|:||.|:..||.:
 Frog   530 LTSELSQARDETKKTHNDILHTENVKSGRDKYKTLRQIRQGNTKQRIDEFEAM 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mer	NP_001285458.1	B41	14..216	CDD:214604	109/201 (54%)
		FERM_C_ERM	210..306	CDD:270015	58/95 (61%)
		ERM	341..635	CDD:395622	70/305 (23%)
ezr	NP_001025629.1	B41	7..206	CDD:214604	109/201 (54%)
		FERM_C_ERM	200..296	CDD:270015	58/95 (61%)
		ERM	338..582	CDD:366293	66/298 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D281811at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010