Protein Alignment Mer and Rdx

DIOPT Version :9

• Sequence 1: NP_001285458.1
• Gene: Mer / 32979
• FlyBaseID: FBgn0086384
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_038937380.1
• Gene: Rdx / 315655
• RGDID: 1359472
• Length: 604
• Species: Rattus norvegicus
• Alignment Length: 642
• Identity: 269/642 - (41%)
• Similarity: 386/642 - (60%)
• Gaps: 77/642 - (11%)

  Fly    10 RSLSVRVSTFDSELEFKLEPRASGQDLFDLVCRTIGLRESWYFGLQYVDTRSNVSWLKMEKRVRD 74
            :.::|||:|.|:||||.::|..:|:.|||.|.:|:||||.|:|||||||::...:|||:.|:|..
  Rat     3 KPINVRVTTMDAELEFAIQPNTTGKQLFDQVVKTVGLREVWFFGLQYVDSKGYSTWLKLNKKVTQ 67

  Fly    75 QRVELHASNNVYVFSFYAKFFPENVSEELIQEITQHLFFLQVKQSILSMDIYCRPEASVLLASYA 139
            |.|:   ..|...|.|.||||||:|||||||||||.|||||||::||:.:|||.||.:|||||||
  Rat    68 QDVK---KENPLQFKFRAKFFPEDVSEELIQEITQRLFFLQVKEAILNDEIYCPPETAVLLASYA 129

  Fly   140 VHVQYGPYDYETYKDGMLAGGELLPKGVTDQYQMTPEMWEERIKTWYMDHEPMTRDEVEMEYLKI 204
            |..:||.|:.|.:|.|.||...|||:.|.:|:::|.|.|||||:.|:.:|..|.|::..||||||
  Rat   130 VQAKYGDYNKEIHKPGYLANDRLLPQRVLEQHKLTKEQWEERIQNWHEEHRGMLREDSMMEYLKI 194

  Fly   205 AQDLDMYGVNYFPITNKNKTKLWLGVTSVGLNIYDERDKLTPKTTFQWNEIRHVSFDDKKFTIRL 269
            ||||:|||||||.|.||..|:|||||.::|||||:..||||||..|.|:|||::||:||||.|:.
  Rat   195 AQDLEMYGVNYFEIKNKKGTELWLGVDALGLNIYEHDDKLTPKIGFPWSEIRNISFNDKKFVIKP 259

  Fly   270 VDAKVSNFIFYSQDLHINKMILDLCKGNHDLYMRRRKPDTMEIQQMKAQAKEEKQRRQIERKKFI 334
            :|.|..:|:||:..|.|||.||.||.|||:||||||||||:|:|||||||:|||.::|:||.:..
  Rat   260 IDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERAQLE 324

  Fly   335 REKKLREKAEHERYELEKSMEHLQNEMRMANDALRRSEETKELYFEKSRVNEEQMQLTECKANHF 399
            .|||.||.||.|:..:|:..|.|...:|...:...:::  |||        |||.:    ||...
  Rat   325 NEKKKREIAEKEKERIEREKEELMERLRQIEEQTMKAQ--KEL--------EEQTR----KALEL 375

  Fly   400 KTEMDRLRERQMKIEREKHDLEKKIRDADFYVHQLTVENDKREAETEKLRKELICAKMAEREATA 464
            :.|..|.:|...:::||:...|    :|...:        .::|..:...:|.:.|::||..|..
  Rat   376 EQERQRAKEEAERLDRERRAAE----EAKSAI--------AKQAADQMKNQEQLAAELAEFTAKI 428

  Fly   465 RLLEFLNSGRKSSTDSLLTASSVSHAANTASS------------MAAISTPS----LITSSSTND 513
            .|||   ..:|...:.   |:...|.|..|..            |.|...|.    :..:.:.:|
  Rat   429 ALLE---EAKKKKEEE---ATEWQHKAFAAQEDLEKTKEELKTVMCAPPPPPPPAVVPPTENEHD 487

  Fly   514 LETAGGAELTTHSSHYLVQGDNSSGISDDFEPKEFILTDNEMEQITNEMERNHLDYLRNSKQVQS 578
            .:....||.:...|        |.|:::.         .:|.|::| |.::|        ::|:.
  Rat   488 EQDEHSAEASAELS--------SEGVTNH---------RSEEERVT-ETQKN--------ERVKK 526

  Fly   579 QLQTLRSEIAPHKIEENQSNLDILSEAQIKAGENKYSTLKKLKSGSTKARVAFFEEL 635
            |||.|.||:|..:.|..::..|:|....:|||.:||.||::::.|:||.|:..||.:
  Rat   527 QLQALSSELAQARDETKKTQNDVLHAENVKAGRDKYKTLRQIRQGNTKQRIDEFEAM 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mer	NP_001285458.1	B41	14..216	CDD:214604	116/201 (58%)
		FERM_C_ERM	210..306	CDD:270015	60/95 (63%)
		ERM	341..635	CDD:395622	75/309 (24%)
Rdx	XP_038937380.1	B41	7..206	CDD:214604	116/201 (58%)
		FERM_C_ERM	200..296	CDD:270015	60/95 (63%)
		ERM	347..583	CDD:395622	69/293 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3529
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D281811at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820