Protein Alignment Mer and msna

DIOPT Version :9

• Sequence 1: NP_001285458.1
• Gene: Mer / 32979
• FlyBaseID: FBgn0086384
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: NP_001004296.1
• Gene: msna / 286739
• ZFINID: ZDB-GENE-021211-2
• Length: 579
• Species: Danio rerio
• Alignment Length: 634
• Identity: 265/634 - (41%)
• Similarity: 384/634 - (60%)
• Gaps: 69/634 - (10%)

  Fly    10 RSLSVRVSTFDSELEFKLEPRASGQDLFDLVCRTIGLRESWYFGLQYVDTRSNVSWLKMEKRVRD 74
            :::||||:|.|:||||.::|..:|:.|||.|.:||||||.|:|||||.||:...:|||:.|:|..
Zfish     3 KTISVRVTTMDAELEFAIQPSTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTA 67

  Fly    75 QRVELHASNNVYVFSFYAKFFPENVSEELIQEITQHLFFLQVKQSILSMDIYCRPEASVLLASYA 139
            |.|.   ..:..:|.|.|||:||:||||||||.||.|||||||:.||:.||||.||.:|||||||
Zfish    68 QDVR---KESPLLFKFRAKFYPEDVSEELIQEATQRLFFLQVKEGILNDDIYCPPETAVLLASYA 129

  Fly   140 VHVQYGPYDYETYKDGMLAGGELLPKGVTDQYQMTPEMWEERIKTWYMDHEPMTRDEVEMEYLKI 204
            |..:|..|:.:.:..|.|:..:|||:.|.:|:::..|.|||||:.|:.:|:.|.|::..||||||
Zfish   130 VQAKYADYNKDAHTPGYLSNEKLLPQRVLEQHKLNKEQWEERIQVWHEEHKGMLREDSMMEYLKI 194

  Fly   205 AQDLDMYGVNYFPITNKNKTKLWLGVTSVGLNIYDERDKLTPKTTFQWNEIRHVSFDDKKFTIRL 269
            ||||:|||||||.|.||..::|||||.::|||||::.||:|||..|.|:|||::||:||||.|:.
Zfish   195 AQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDKMTPKIGFPWSEIRNISFNDKKFVIKP 259

  Fly   270 VDAKVSNFIFYSQDLHINKMILDLCKGNHDLYMRRRKPDTMEIQQMKAQAKEEKQRRQIERKKFI 334
            :|.|..:|:||:|.|.|||.||.||.|||:||||||||||:|:|||||||||||..:::||....
Zfish   260 IDKKAPDFVFYAQRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAKEEKNHKKMERALLE 324

  Fly   335 REKKLREKAEHERYELEKSMEHLQNEMRMANDALRRSEETKELYFEKSRVNEEQMQLTECKANHF 399
            .|:|.||:||.|:.::||..|.|...:|:..:..|::::  ||        |||.:    ||...
Zfish   325 DERKKREQAEKEKEKIEKEKEELMERLRVIEEQTRKAQQ--EL--------EEQTR----KALEL 375

  Fly   400 KTEMDRLRERQMKIEREKHDLEKKIRDADFYVHQLTVENDKREAETEKLRKELICAKMAEREATA 464
            :.|..|.:|...::|||:. |.::.:.|..           :::|::...:|.:..::||..:..
Zfish   376 EQERKRAQEEAERLERERR-LAEEAKSALL-----------QQSESQMKNQEHLATELAELTSKI 428

  Fly   465 RLLEFLNSGRKSSTDSLLTASSVSHAANTASSMAAISTPSLITSSSTNDLE-TAGGAELTTHSSH 528
            .|||   ..:|...|..|       ...|.::|.            ..||| |....:....|||
Zfish   429 SLLE---DAKKKKEDEAL-------EWQTKATMV------------QEDLEKTKEELKNKVMSSH 471

  Fly   529 YL--VQGDNSSGISDDFEPKEFI-LT------DNEMEQITNEMERNHLDYLRNSKQVQSQLQTLR 584
            ..  |.|:|.:...|:...:... ||      |...|:...|.|:|        ::||..|..|.
Zfish   472 VTEPVHGENDNDEGDESSAEASAELTSAAAYKDRSEEERMTEAEKN--------ERVQKHLLALT 528

  Fly   585 SEIAPHKIEENQSNLDILSEAQIKAGENKYSTLKKLKSGSTKARVAFFE 633
            ||:|..:.|..::..||:....::||.:||.||::::||:||.|:..||
Zfish   529 SELANARDETKKTQNDIIHAENVRAGRDKYKTLRQIRSGNTKQRIDEFE 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mer	NP_001285458.1	B41	14..216	CDD:214604	110/201 (55%)
		FERM_C_ERM	210..306	CDD:270015	59/95 (62%)
		ERM	341..635	CDD:395622	78/303 (26%)
msna	NP_001004296.1	B41	7..206	CDD:214604	110/201 (55%)
		FERM_N	9..71	CDD:286467	33/61 (54%)
		FERM_M	91..206	CDD:278785	65/114 (57%)
		FERM_C_ERM	200..296	CDD:270015	59/95 (62%)
		ERM	347..579	CDD:279153	71/287 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3529
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D281811at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820