Protein Alignment Mer and LOC100485014

DIOPT Version :9

• Sequence 1: NP_001285458.1
• Gene: Mer / 32979
• FlyBaseID: FBgn0086384
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_012812993.1
• Gene: LOC100485014 / 100485014
• -ID: -
• Length: 635
• Species: Xenopus tropicalis
• Alignment Length: 615
• Identity: 233/615 - (37%)
• Similarity: 358/615 - (58%)
• Gaps: 62/615 - (10%)

  Fly     7 KKNRSLSVRVSTFDSELEFKLEPRASGQDLFDLVCRTIGLRESWYFGLQYVDTRSNVSWLKMEKR 71
            |:.::..|::.|.|||:|...|....|..||.|.|.|:||:|||:||||:.....: :|||::|:
 Frog     9 KQLKNFRVKIMTMDSEMELTCEMNWKGSVLFGLACETLGLKESWFFGLQFTSNGMD-TWLKLDKK 72

  Fly    72 VRDQRVELHASNNVYVFSFYAKFFPENVSEELIQEITQHLFFLQVKQSILSMDIYCRPEASVLLA 136
            :..|.:.......   |.|.|||:||||:|||:|:||:||||||||:.||..:|:|.||||||||
 Frog    73 ILQQDLPKEEPTK---FRFLAKFYPENVAEELVQDITRHLFFLQVKKQILDEEIHCLPEASVLLA 134

  Fly   137 SYAVHVQYGPYDYETYKDGMLAGGELLPKGVTDQYQMTPEMWEERIKTWYMDHEPMTRDEVEMEY 201
            .:|:..:||.|:...::.|.|:..||||:.|..|||||.|||:|:|..||.:|....|||.||.|
 Frog   135 LFALQAKYGDYNPNIHQPGFLSKDELLPQRVLQQYQMTSEMWQEKITAWYAEHRGTDRDEAEMNY 199

  Fly   202 LKIAQDLDMYGVNYFPITNKN-KTKLWLGVTSVGLNIYDERDKLTPKTTFQWNEIRHVSFDDKKF 265
            |||||||||:|:|||||:..| .:.:.|||.:.|::|:...:|:.|..:|:|.:||:::::.||.
 Frog   200 LKIAQDLDMFGMNYFPISQSNTDSNILLGVNAKGIHIFSINNKIIPLKSFKWGDIRNINYNYKKL 264

  Fly   266 TIRLVDAKVSNFIFYSQDLHINKMILDLCKGNHDLYMRRRKPDTMEIQQMKAQAKEEKQRRQIER 330
            .|..:..|...|.|||....::|:|.|||.|||.|:|.:||.|:.:|||||.|||.|:.|::||.
 Frog   265 KIIPISRKEDVFKFYSSGHKVDKLIYDLCTGNHRLFMTKRKVDSKDIQQMKNQAKLERTRKKIEH 329

  Fly   331 KKFIREKKLREKAEHERYELEKSMEHLQNEMRMANDALRRSEETKELYFEKSRVNEEQMQLTECK 395
            :..:|||:|||.||..:.::|:.:..|::|.|.||:||..|.||.||..||:::.||:.:|....
 Frog   330 QNLLREKQLREDAERAKEDMERRLFQLEDEARQANEALICSNETAELMAEKAQIAEEEAKLLAQN 394

  Fly   396 ANHFKTEMDRLRERQMKIEREKHDLEKKIRDADFYVHQLTVENDKREAETEKLRKELICAKMAER 460
            |...:.||.||....:|.:.|...:|:|:|:||....:|..|:|:|..|.|:|.::|..|:.|||
 Frog   395 AVETRQEMQRLEISVLKSKEEMQLMEQKMREADMITVKLIKESDRRAKEAEQLEQDLRKAREAER 459

  Fly   461 EATARLLEFLNSGRKSSTDSLLTASSVSHAANTASSMAAISTPSLITSSSTNDLETAGGAELTTH 525
            .|..||::                     .::....:||...|..:|
 Frog   460 NAKQRLMD---------------------VSSLCQPLAAKCFPLDVT------------------ 485

  Fly   526 SSHYLVQGDNSSGISDDFEPKEFI---LTDNEMEQITNEMERNHLDYLRNSKQVQSQLQTLRSEI 587
                           |.|.....|   .:|.::::::.|:|:..||||..|:|::|||..|::|:
 Frog   486 ---------------DGFIENRIISLDASDTDIKRLSLEIEKERLDYLEKSRQLESQLNDLKTEL 535

  Fly   588 APHKIEENQSNLDILSEAQIKAGENKYSTL 617
            ...|.|:.|.:|..|....:::.::.:..|
 Frog   536 RTLKREDRQLSLQSLWNGTLRSKDHLHDPL 565

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mer	NP_001285458.1	B41	14..216	CDD:214604	103/201 (51%)
		FERM_C_ERM	210..306	CDD:270015	37/96 (39%)
		ERM	341..635	CDD:395622	75/280 (27%)
LOC100485014	XP_012812993.1	B41	15..214	CDD:214604	103/202 (51%)
		PH-like	208..305	CDD:388408	37/96 (39%)
		ERM	340..544	CDD:366293	71/257 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	115	1.000	Domainoid score	I5958
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D281811at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm47465
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4049
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010