Protein Alignment Mer and msn

DIOPT Version :9

• Sequence 1: NP_001285458.1
• Gene: Mer / 32979
• FlyBaseID: FBgn0086384
• Length: 635
• Species: Drosophila melanogaster
• Sequence 2: XP_002936828.1
• Gene: msn / 100145669
• XenbaseID: XB-GENE-1004600
• Length: 580
• Species: Xenopus tropicalis
• Alignment Length: 643
• Identity: 261/643 - (40%)
• Similarity: 378/643 - (58%)
• Gaps: 82/643 - (12%)

  Fly    10 RSLSVRVSTFDSELEFKLEPRASGQDLFDLVCRTIGLRESWYFGLQYVDTRSNVSWLKMEKRVRD 74
            :::||||:|.|:||||.::|..:|:.|||.|.:||||||.|:|||||.||:...:|||:.|:|..
 Frog     3 KTISVRVTTMDAELEFAIQPNTTGKQLFDQVVKTIGLREVWFFGLQYQDTKGFSTWLKLNKKVTA 67

  Fly    75 QRVELHASNNVYVFSFYAKFFPENVSEELIQEITQHLFFLQVKQSILSMDIYCRPEASVLLASYA 139
            |.|.   .::..:|.|.|||:||:|||||||:|||.|||||||:.||:.||||.||.:|||||||
 Frog    68 QDVR---KDSPLLFKFRAKFYPEDVSEELIQDITQRLFFLQVKEGILNDDIYCPPETAVLLASYA 129

  Fly   140 VHVQYGPYDYETYKDGMLAGGELLPKGVTDQYQMTPEMWEERIKTWYMDHEPMTRDEVEMEYLKI 204
            |..:||.|:.|..|.|.|:|.:|||:.|.:|::::.:.|||||..|:.:|..|.|::..:|||||
 Frog   130 VQAKYGDYNKECQKPGYLSGDKLLPQRVLEQHKLSKDQWEERIHVWHEEHRGMLREDAILEYLKI 194

  Fly   205 AQDLDMYGVNYFPITNKNKTKLWLGVTSVGLNIYDERDKLTPKTTFQWNEIRHVSFDDKKFTIRL 269
            ||||:|||||||.|.||..::|||||.::|||||::.|:||||..|.|:|||::||:||||.|:.
 Frog   195 AQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYEQNDRLTPKIGFPWSEIRNISFNDKKFVIKP 259

  Fly   270 VDAKVSNFIFYSQDLHINKMILDLCKGNHDLYMRRRKPDTMEIQQMKAQAKEEKQRRQIERKKFI 334
            :|.|..:|:||:..|.|||.||.||.|||:||||||||||:|:|||||||:|||.::|:||....
 Frog   260 IDKKAPDFVFYAPRLRINKRILALCMGNHELYMRRRKPDTIEVQQMKAQAREEKHQKQMERALLE 324

  Fly   335 REKKLREKAEHERYELEKSMEHLQNEMRMANDALRRSEETKELYFEKSRVNEEQMQLTECKANHF 399
            .|||.||.||.|:.::|:..|.|...:|...|..|:::|..|   |::|           ||...
 Frog   325 NEKKKRELAEKEKEKIEREKEELMERLRQIEDQTRKAQEALE---EQTR-----------KALEL 375

  Fly   400 KTEMDRLRERQMKIEREKHDLEKKIRDADFYVHQLTVENDK----REAETEKLRKELICAKMAER 460
            :.|..|.:|...|:.||:                |..|..|    ::::.:...:|.:.|:::..
 Frog   376 EDERRRAQEEAEKLARER----------------LAAEEAKEALLKQSQDQMKNQEHLAAELSAL 424

  Fly   461 EATARLLEFLNSGRKSSTDSLLTASSVSHAANTASS------------MAAISTPSLITSSSTND 513
            .||...|||....::      |.|......|:...:            |.....|..:.:.:.:|
 Frog   425 TATISQLEFARQKKE------LEAQEWQDKAHNVQADLEKTQEELKLVMTTPHVPEPVHAENEHD 483

  Fly   514 LETAGGAELTTHSSHYLVQGDNSSGISDDFEPK-EFILTDNEMEQITNEMERNHLDYLRNSKQVQ 577
            .|                  ||.:......|.| |.::.|...|..|.|.|:|        ::||
 Frog   484 DE------------------DNENNAEASAELKSEAMIKDRSEEDRTTEAEKN--------ERVQ 522

  Fly   578 SQLQTLRSEIAPHKIEENQSNLDILSEAQIKAGENKYSTLKKLKSGSTKARVAFFEEL 635
            ..|..|.||:|..:.|..::..|:|....::||.:||.||::::.|:||.|:..||.:
 Frog   523 KHLLLLSSELANARDETKKTANDLLHAENVRAGRDKYKTLRQIRQGNTKQRIDEFESM 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mer	NP_001285458.1	B41	14..216	CDD:214604	112/201 (56%)
		FERM_C_ERM	210..306	CDD:270015	58/95 (61%)
		ERM	341..635	CDD:395622	72/310 (23%)
msn	XP_002936828.1	B41	7..206	CDD:214604	112/201 (56%)
		FERM_C_ERM	200..296	CDD:270015	58/95 (61%)
		ERM	347..580	CDD:366293	66/294 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D281811at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010