Protein Alignment CG14227 and TMPRSS3

DIOPT Version :9

• Sequence 1: NP_608345.2
• Gene: CG14227 / 32978
• FlyBaseID: FBgn0031058
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: NP_076927.1
• Gene: TMPRSS3 / 64699
• HGNCID: 11877
• Length: 454
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 71/288 - (24%)
• Similarity: 119/288 - (41%)
• Gaps: 56/288 - (19%)

  Fly    20 REGSA-----FLLDAECGRSLPTNAKLTWWNYFDSSTDIQANPWIVSVIVNGKAKCSGSLINHRF 79
            |||.|     .|....||.....::::...|    .:.:...||..|:...|...|.||:|...:
Human   191 REGCASGHVVTLQCTACGHRRGYSSRIVGGN----MSLLSQWPWQASLQFQGYHLCGGSVITPLW 251

  Fly    80 VLTAAHCVFREAMQVHLGDFDAWNPGQ---NCSSGARLSNAYCVRIDKKIVHAGFGKIQAQQYDI 141
            ::||||||           :|.:.|..   .....:.|.|.....:.:|||:....|.:....||
Human   252 IITAAHCV-----------YDLYLPKSWTIQVGLVSLLDNPAPSHLVEKIVYHSKYKPKRLGNDI 305

  Fly   142 GLLRMQHAVQYSDFVRPICLLINEPVAAIDRFQ------LTVWGTTAEDFRSIPRVLKHSVGDRI 200
            .|:::...:.:::.::|:||..:|     :.|.      .:.||.|.:.......||.|:....|
Human   306 ALMKLAGPLTFNEMIQPVCLPNSE-----ENFPDGKVCWTSGWGATEDGAGDASPVLNHAAVPLI 365

  Fly   201 DRELCTLK--FQQQVDESQICVHTETS--HACKGDSGGPFSAK-----ILYGGTYRTFQFGIIIF 256
            ..::|..:  :...:..|.:|....|.  .:|:||||||...:     .|.|.|    .|||
Human   366 SNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQERRLWKLVGAT----SFGI--- 423

  Fly   257 GLSSCAGLS---VCTNVTFYMDWIWDAL 281
               .||.::   |.|.||.::|||.:.:
Human   424 ---GCAEVNKPGVYTRVTSFLDWIHEQM 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	61/240 (25%)
		Tryp_SPc	57..277	CDD:238113	61/240 (25%)
TMPRSS3	NP_076927.1	LDLa	74..107	CDD:238060
		SRCR_2	112..210	CDD:292133	7/18 (39%)
		Tryp_SPc	216..444	CDD:214473	62/257 (24%)
		Tryp_SPc	217..447	CDD:238113	64/259 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910