DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14227 and Tmprss11d

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_001028824.2	Gene:	Tmprss11d / 64565	RGDID:	620654	Length:	417	Species:	Rattus norvegicus

Alignment Length:	283	Identity:	78/283 - (27%)
Similarity:	120/283 - (42%)	Gaps:	69/283 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LLDAECGRSLP-------------TNAKLTWWNYFDSSTDIQANPWIVSVIVNGKAKCSGSLINH 77
            :|..||| :.|             |.|:...|            ||.||:.:|....|.|:||::
  Rat   167 VLTQECG-ARPDLITLSEERIIGGTQAETGDW------------PWQVSLQLNNVHHCGGTLISN 218

  Fly    78 RFVLTAAHCVFREAMQVHLGDFDAWNPGQ-NCSSG-ARLSNAYCVRIDKKIVHAGFGKIQAQQYD 140
            .:||||||| ||...          ||.| ..:.| :.:|....||:...:.||.:..| .:..|
  Rat   219 LWVLTAAHC-FRSYS----------NPQQWTATFGVSTISPRLRVRVRAILAHAEYNSI-TRDND 271

  Fly   141 IGLLRMQHAVQYSDFVRPICL------LINEPVAAIDRFQLTVWGTTAEDFRSIPRVLKHSVGDR 199
            |.::::...|.::..:..:||      :|.:.||.:     |.||:......::..:.:..|  |
  Rat   272 IAVVQLDRPVTFTRNIHRVCLPAATQNIIPDSVAYV-----TGWGSLTYGGNTVTNLQQGEV--R 329

  Fly   200 I-DRELCT--LKFQQQVDESQIC--VHTETSHACKGDSGGPFSAKILYGGTYRT-FQFGIIIFGL 258
            | ..|:|.  ..:...|....:|  |.:....||:||||||    ::...|.|. |..||:.:|.
  Rat   330 IVSSEVCNEPAGYGGSVLPGMLCAGVRSGAVDACQGDSGGP----LVQEDTRRLWFVVGIVSWGY 390

  Fly   259 SSCAGL----SVCTNVTFYMDWI 277
            .  .||    .|.|.||.|.:||
  Rat   391 Q--CGLPNKPGVYTRVTAYRNWI 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	68/237 (29%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	68/237 (29%)
Tmprss11d	NP_001028824.2	SEA	48..150	CDD:396113
Tmprss11d	NP_001028824.2	Tryp_SPc	186..414	CDD:238113	73/263 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910