DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14227 and proz

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_001116189.1	Gene:	proz / 496781	XenbaseID:	XB-GENE-971425	Length:	416	Species:	Xenopus tropicalis

Alignment Length:	258	Identity:	51/258 - (19%)
Similarity:	100/258 - (38%)	Gaps:	51/258 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 LGSREGSAFLLDA-ECGRSLPTNAKLTWWNYFDSSTDIQAN--PWIVSVIVNGKAK-CSGSLINH 77
            ||:.|.|....|. .||:.|.....:|     .:...:||:  ||.|.|:.:.|.: |||.:::.
Frog   160 LGADEKSCHPEDPFACGQILNLEVSIT-----KNRNHLQADIFPWQVPVLNSQKVQVCSGVVLSE 219

  Fly    78 RFVLTAAHCVFREAMQVHLGDFDAWNP-----GQNCSSGARLSNAYCVRIDKKIVHAGFGKIQAQ 137
            ..|||.|.|:            ..::|     |....||  |.....:|:..|.||..:.: :..
Frog   220 SVVLTTASCI------------TMYDPYFVVAGVQQKSG--LGQRQMIRVKTKQVHMRYSE-ETG 269

  Fly   138 QYDIGLLRMQHAVQYSDFVRPICL----LINEPVAAIDRFQLTVWGTTAEDFRSIPRVLKHSVGD 198
            ..:|.||:::..:.:.:...|||:    .....:...:...::.|.:::|              :
Frog   270 DNNIALLKLKEKIVFHNNSLPICIPQKDFAENVLVPFNTGLVSGWKSSSE--------------E 320

  Fly   199 RIDRELCTLKFQQQVDESQICVH----TETSHACKGDSGGPFSAKILYGGTYRTFQFGIIIFG 257
            ..|..:....:.:..:.:::|..    |:|:....|.|.....:::..||.......|:...|
Frog   321 EADALIPIQFYTKYTNRTEVCEQSLNVTQTNRMFCGVSHEAIDSELSEGGHLAVQHNGVWFLG 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	40/215 (19%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	40/215 (19%)
proz	NP_001116189.1	GLA	22..85	CDD:214503
		EGF_CA	92..123	CDD:238011
		FXa_inhibition	136..167	CDD:373209	3/6 (50%)
		Tryp_SPc	197..414	CDD:389826	40/216 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910