DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14227 and masp2

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_001011037.1	Gene:	masp2 / 496446	XenbaseID:	XB-GENE-1007491	Length:	687	Species:	Xenopus tropicalis

Alignment Length:	271	Identity:	68/271 - (25%)
Similarity:	113/271 - (41%)	Gaps:	45/271 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ECGRSLPTNAKLTWWNYFDSSTDIQANPWIVSVIVNGKAKCSGSLINHRFVLTAAHCVFR----E 90
            :||:..|..|.......|   .::...||.|.:..|.: :..|:|:...::|||||.|:.    .
Frog   432 DCGKRKPAAAGRIVGGEF---ANVGEFPWQVFINANNE-RGGGALLLDNWILTAAHVVYSYDDLS 492

  Fly    91 AMQVHLGDFDAWNPGQNCSSGARLSNAYCVRIDKKIVHAGFGKIQAQQYDIGLLRMQHAVQYS-D 154
            ::.:.:|.....:           ||......:...:|.|: |......||.|:::::.|..| :
Frog   493 SILIKMGFLSTQD-----------SNYIRGWPEAVFIHEGY-KPGHYNNDIALIKLKNKVPLSEE 545

  Fly   155 FVRPICLLINEPVAAIDRFQ-------LTVWGTTAEDFRSIPRVLKHSVGDRIDRELCTLKF--- 209
            .:..|||...|....|....       :..||.| |..|| .|.|:....:.:|...|..::
Frog   546 SILGICLPTKEKSYHISHKDDDNHVGLVAGWGLT-EAQRS-SRKLRFVEVNIVDHSTCKAEYAKL 608

  Fly   210 --QQQVDESQICVHTE--TSHACKGDSGGPFSAKILYGGTYRTFQFGIIIFGLSSCAGLS----V 266
              |..|.|:.||...|  ...:|.|||||..:  .:...:.:.|..||:.:|:.  .|::    |
Frog   609 DAQYIVTENMICAGFEIGVKDSCAGDSGGALA--FMNAESKKWFVGGIVSWGVG--CGVARQYGV 669

  Fly   267 CTNVTFYMDWI 277
            .|.||.|:|||
Frog   670 YTKVTNYLDWI 680

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	61/242 (25%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	61/242 (25%)
masp2	NP_001011037.1	CUB	30..139	CDD:238001
		FXa_inhibition	145..180	CDD:317114
		CUB	184..294	CDD:238001
		CCP	299..361	CDD:153056
		CCP	365..430	CDD:153056
		Tryp_SPc	443..680	CDD:214473	62/258 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910