DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14227 and AgaP_AGAP012502

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	XP_001230484.2	Gene:	AgaP_AGAP012502 / 4578454	VectorBaseID:	AGAP012502	Length:	829	Species:	Anopheles gambiae

Alignment Length:	225	Identity:	57/225 - (25%)
Similarity:	99/225 - (44%)	Gaps:	24/225 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 CSGSLINHRFVLTAAHCV-FREAMQ----VHLGDFDAWNPGQNCSSGARLSNAYCVRIDKKIVHA 129
            |.||||...|:||||||. .|:.:.    :.:||.:.::..::    |.:.....:|:.:..::
Mosquito    46 CGGSLIWANFILTAAHCTKDRDTLLPPDIIRIGDLNLYDDRED----ALVQERTIIRVIRHPLY- 105

  Fly   130 GFGKIQAQQYDIGLLRMQHAVQYSDFVRPICLLINEPVAAIDRFQLTVWGTTAEDFRSIPRVLKH 194
               ...:..|||.||.:...|.....|.|.||.:::.: ...:.:...|||:...:.....::|.
Mosquito   106 ---NTSSVFYDIALLMLNEKVNIYFEVMPTCLWLDDNI-PFSKVEAAGWGTSGFGYGKTNILIKA 166

  Fly   195 SVGDRIDRELCTLKFQQQVD------ESQICVHTETSHACKGDSGGPFSAKILYGGTYRTFQFGI 253
            .:....::: |...:.|...      |.|:|...:....|.||||||...|:::|.....|..|:
Mosquito   167 ELKLMANKD-CESYYSQVASVKNGLMEHQLCAWDKVMDTCPGDSGGPLQHKLIFGDYKVPFLVGV 230

  Fly   254 IIFGLSSCAGL--SVCTNVTFYMDWIWDAL 281
            ..||| ||...  .|...|:.:..||.:.|
Mosquito   231 TSFGL-SCGNSQPGVYVKVSKFGSWIVETL 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	54/219 (25%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	54/219 (25%)
AgaP_AGAP012502	XP_001230484.2	Tryp_SPc	19..258	CDD:238113	56/222 (25%)
		Tryp_SPc	19..255	CDD:214473	54/219 (25%)
		Tryp_SPc	325..>418	CDD:304450
		Trypsin	621..823	CDD:278516
		Tryp_SPc	629..826	CDD:304450
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910