DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14227 and proca

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_956650.1	Gene:	proca / 393327	ZFINID:	ZDB-GENE-060824-5	Length:	434	Species:	Danio rerio

Alignment Length:	289	Identity:	75/289 - (25%)
Similarity:	124/289 - (42%)	Gaps:	63/289 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 DAECGR-SLPTNAKLTWWNYFDSSTDIQANPWIV-------------SVIVN--GKAKCSGSLIN 76
            ||.||: .:|.:|      |.:....: ..||::             ::|:|  |:..|.|.||:
Zfish   170 DASCGQIRIPKSA------YANKPKPV-LQPWVMGGNVGKRGESPWQALILNHLGRFHCGGVLID 227

  Fly    77 HRFVLTAAHCVFREA-MQVHLGDFDAWNPGQNCSSGARLSNAYCVRIDKKIVHAGFGKIQAQQYD 140
            ..:|||||||:...: ..|.|||:..:.     ..|:.::    :.:.:.|.|..:..|.... |
Zfish   228 ENWVLTAAHCLETSSKFSVRLGDYQRFK-----FEGSEVT----LPVKQHISHPQYNPITVDN-D 282

  Fly   141 IGLLRMQHAVQYSDFVRPICLLINEPVAAIDRFQL---------TVWGTTAEDFRSIPRVLKHSV 196
            |.|||:...|::|.::.|.||    |...:.:..|         |.||...:...|....|.:..
Zfish   283 IALLRLDGPVKFSTYILPACL----PSLELAKRMLHRNGTVTIITGWGKNNQSATSYNSTLHYVE 343

  Fly   197 GDRIDRELCTLKFQQQVDESQIC--VHTETSHACKGDSGGPFSAKILYGGTYRTFQFGIIIFGLS 259
            ...:|.:.|:......:.::.:|  |..:...||:||||||...  |:..|:  |..|::.:| .
Zfish   344 LPIVDNKECSRHMMNNLSDNMLCAGVLGQVKDACEGDSGGPMMT--LFHDTW--FLVGLVSWG-E 403

  Fly   260 SCA---GLSVCTNVTFYMDWI------WD 279
            .|.   .|.:.|.|..|:|||      ||
Zfish   404 GCGQRDKLGIYTKVASYLDWIDSVRQGWD 432

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	64/249 (26%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	64/249 (26%)
proca	NP_956650.1	GLA	23..84	CDD:214503
		EGF_CA	85..119	CDD:238011
		FXa_inhibition	128..165	CDD:291342
		Tryp_SPc	195..427	CDD:238113	64/250 (26%)
		Tryp_SPc	197..424	CDD:214473	62/245 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910