Protein Alignment CG14227 and KLK2

DIOPT Version :9

• Sequence 1: NP_608345.2
• Gene: CG14227 / 32978
• FlyBaseID: FBgn0031058
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 67/241 - (27%)
• Similarity: 113/241 - (46%)
• Gaps: 32/241 - (13%)

  Fly    55 ANPWIVSVIVNGKAKCSGSLINHRFVLTAAHCVFREAMQVHLGDFDAWNPGQNCSSGARLSNA-- 117
            :.||.|:|..:|.|.|.|.|::.::|||||||: ::..||.||..:.:.| ::......:|::
Human    35 SQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCL-KKNSQVWLGRHNLFEP-EDTGQRVPVSHSFP 97

  Fly   118 ---YCVRIDKKIVHAGFGKIQAQQYDIGLLRMQHAVQYSDFVRPICLLINEPVAAIDRFQLTVWG 179
               |.:.:.|   |......:...:|:.|||:....:.:|.|:.:.|...||......: .:.||
Human    98 HPLYNMSLLK---HQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQEPALGTTCY-ASGWG 158

  Fly   180 T-TAEDF---RSIPRVLKHSVGDRIDRELCTLKFQQQVDESQIC--VHTETSHACKGDSGGPFSA 238
            : ..|:|   ||:..|..|    .:..::|...:.::|.|..:|  :.|.....|.||||||
Human   159 SIEPEEFLRPRSLQCVSLH----LLSNDMCARAYSEKVTEFMLCAGLWTGGKDTCGGDSGGP--- 216

  Fly   239 KILYGGTYRTFQFGIIIFGLSSCA---GLSVCTNVTFYMDWIWDAL 281
             ::..|..:    ||..:|...||   ..:|.|.|..|..||.|.:
Human   217 -LVCNGVLQ----GITSWGPEPCALPEKPAVYTKVVHYRKWIKDTI 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	64/233 (27%)
		Tryp_SPc	57..277	CDD:238113	64/233 (27%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	66/238 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910