Protein Alignment CG14227 and KLK1

DIOPT Version :9

• Sequence 1: NP_608345.2
• Gene: CG14227 / 32978
• FlyBaseID: FBgn0031058
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: NP_002248.1
• Gene: KLK1 / 3816
• HGNCID: 6357
• Length: 262
• Species: Homo sapiens
• Alignment Length: 298
• Identity: 74/298 - (24%)
• Similarity: 118/298 - (39%)
• Gaps: 60/298 - (20%)

  Fly     9 LILFASLFLGSREGSAFLLDAECGRSLPTNAKLT--WWNYFDSSTDIQANPWIVSVIVNGKAKCS 71
            |:|..:|.||.           .|.:.|..:::.  |      ..:..:.||..::......:|.
Human     4 LVLCLALSLGG-----------TGAAPPIQSRIVGGW------ECEQHSQPWQAALYHFSTFQCG 51

  Fly    72 GSLINHRFVLTAAHCVFREAMQVHLGD---FDAWNPGQNCSSGARLSNAYCVRIDKKIVHAGFGK 133
            |.|::.::|||||||: .:..|:.||.   ||..|..|            .|.:.:...|.||..
Human    52 GILVHRQWVLTAAHCI-SDNYQLWLGRHNLFDDENTAQ------------FVHVSESFPHPGFNM 103

  Fly   134 I-------QAQQ---YDIGLLRM-QHAVQYSDFVRPICLLINEPVAAIDRFQLTVWGTTAEDFRS 187
            .       ||.:   :|:.|||: :.|...:|.|:.:.|...||... .....:.||:...:..|
Human   104 SLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPTEEPEVG-STCLASGWGSIEPENFS 167

  Fly   188 IPRVLKHSVGDRIDRELCTLKFQQQVDESQICV-HTE-TSHACKGDSGGPFSAKILYGGTYRTFQ 250
            .|..|:......:..:.|.....|:|.:..:|| |.| ....|.||||||    ::..|..:
Human   168 FPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLEGGKDTCVGDSGGP----LMCDGVLQ--- 225

  Fly   251 FGIIIFGLSSCA---GLSVCTNVTFYMDWIWDALVNLS 285
             |:..:|...|.   ..||...|..|:.||.|.:...|
Human   226 -GVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIAENS 262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	62/238 (26%)
		Tryp_SPc	57..277	CDD:238113	62/238 (26%)
KLK1	NP_002248.1	Tryp_SPc	25..257	CDD:238113	65/259 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910