DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14227 and Tmprss4

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	XP_038937788.1	Gene:	Tmprss4 / 367074	RGDID:	1305033	Length:	478	Species:	Rattus norvegicus

Alignment Length:	283	Identity:	88/283 - (31%)
Similarity:	135/283 - (47%)	Gaps:	51/283 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 GSR---EGSAFLLDA-ECGRSLPTNAKLTWWNYFDSSTDIQANPWIVSVIVNGKAKCSGSLINHR 78
            |||   .||...|.. :||:||.|...:   ...::|.|  :.||.||:..|.:..|.||:::|.
  Rat   220 GSRSCLSGSLVSLRCLDCGKSLKTTRVV---GGVEASAD--SWPWQVSIQYNKQHVCGGSILDHH 279

  Fly    79 FVLTAAHCVFREAMQVHLGDFDAW--NPGQNCSSGARLSNAYCVRIDKKIVHAGFGKIQAQQYDI 141
            ::|||||| ||:.:     |..:|  ..|.|     :|.|:..:.: .||..|....:|.::.||
  Rat   280 WILTAAHC-FRKYL-----DVSSWKVRAGSN-----KLGNSPSLPV-AKIFIAEPNPLQPKEKDI 332

  Fly   142 GLLRMQHAVQYSDFVRPICLLINE-------PVAAIDRFQLTVWGTTAEDFRSIPRVLKHSVGDR 199
            .|::::..:.:|..||||||..::       ||..|.      ||.|.|:...:...|..:....
  Rat   333 ALVKLKMPLTFSGSVRPICLPFSDEELIPTMPVWVIG------WGFTEENGGKMSDTLLQASVQV 391

  Fly   200 IDRELCTLK--FQQQVDESQICVHTET--SHACKGDSGGPFSAKILYGGTYRTFQ-FGIIIFGLS 259
            ||...|..:  :|.:|....:|..|..  ...|:||||||    ::|  .|..:| .||:.:|.
  Rat   392 IDSARCNAEDAYQGEVTAGMLCAGTPQGGKDTCQGDSGGP----LMY--HYDKWQVVGIVSWGY- 449

  Fly   260 SCAGLS---VCTNVTFYMDWIWD 279
            .|...|   |.|.||.|:|||::
  Rat   450 GCGSPSTPGVYTKVTAYLDWIYN 472

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	73/236 (31%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	73/236 (31%)
Tmprss4	XP_038937788.1	LDLa	99..133	CDD:238060
		SRCR_2	149..238	CDD:413346	6/17 (35%)
		Tryp_SPc	245..470	CDD:214473	75/254 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910