DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14227 and SPH93

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_609840.1	Gene:	SPH93 / 35049	FlyBaseID:	FBgn0032638	Length:	494	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	72/277 - (25%)
Similarity:	118/277 - (42%)	Gaps:	29/277 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 GSAFLLDAECGRSLPTNAKLTWWNYFDSSTDIQANPWIVSVIVNGKAKCSGSLINHRFVLTAAHC 86
            ||:.||...||.|.....::......|.:...| .||.|::..||:....||||....|||.||.
  Fly   224 GSSELLSPSCGMSNANGLQMVEGITIDQARPAQ-YPWAVAIFHNGQYLAGGSLIQPNVVLTVAHR 287

  Fly    87 V--FREAMQVHLGDFDAWNPGQNCSSGARLSNAYCVRIDKKIVHAGFGKIQAQQYDIGLLRMQHA 149
            |  ....:.|..||:|..:..:...|..|       .:::.::|.|| ..::...::.||.:...
  Fly   288 VITIETELVVRAGDWDLKSDREIFLSEQR-------EVERAVIHEGF-DFKSGANNLALLFLNSP 344

  Fly   150 VQYSDFVRPICLLINEPVAAIDRFQLTVWGTTAEDFRSIPRVLKHSVGDRIDRELCTLKFQQ--- 211
            .:.:|.:|.|||.......|..|..:..||....:.:....|||......::|.:|. ||.:
  Fly   345 FKLNDHIRTICLPTPNKSFAGRRCTVAGWGKMRYEDQRYSTVLKKVQLLVVNRNVCE-KFLRSTR 408

  Fly   212 -----QVDESQICVHTETSH-ACKGDSGGPFSAKI--LYGGTYRTFQFGIIIFGLSSCA--GL-S 265
                 ::.::.||...|... .|.||.|......|  ...|.|.  |.||:.:|: .|.  |: :
  Fly   409 LGAKFELPKNIICAGGELGRDTCTGDGGSALFCSIGGENSGVYE--QAGIVNWGV-GCGQEGIPA 470

  Fly   266 VCTNVTFYMDWIWDALV 282
            :.|.|:.:.:||.:.|:
  Fly   471 IYTEVSKFTNWITEKLL 487

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	60/235 (26%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	60/235 (26%)
SPH93	NP_609840.1	GRP	<136..189	CDD:254089
		Tryp_SPc	250..485	CDD:238113	64/247 (26%)
		Tryp_SPc	252..482	CDD:214473	61/242 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010