DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14227 and l(2)k05911

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_723797.3	Gene:	l(2)k05911 / 34731	FlyBaseID:	FBgn0284244	Length:	639	Species:	Drosophila melanogaster

Alignment Length:	297	Identity:	86/297 - (28%)
Similarity:	124/297 - (41%)	Gaps:	77/297 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 SREGSAFLLDAECGRSLPTNAKLTWWNYFDSST---DIQAN----PWIVSVIVNGKAKCSGSLIN 76
            |.||    |..:||...|...        |...   .|.|:    |||..:..:||..|.||||.
  Fly   379 SSEG----LPLQCGNKNPVTP--------DQERIVGGINASPHEFPWIAVLFKSGKQFCGGSLIT 431

  Fly    77 HRFVLTAAHCVFR------EAMQVHLGDFDAWNPG-----QNCSSGARLSNAYCVRIDKKIVHAG 130
            :..:|||||||.|      .|:..||||:   |.|     |:.|.          ||.:.:.|.|
  Fly   432 NSHILTAAHCVARMTSWDVAALTAHLGDY---NIGTDFEVQHVSR----------RIKRLVRHKG 483

  Fly   131 FGKIQAQQYDIGLLRMQHAVQYSDFVRPICLLINEPVAAIDRFQ------LTV--WGTTAEDFRS 187
            | :......|:.:|.:...|.::..::||||    |.:...:.:      .||  ||:..|:...
  Fly   484 F-EFSTLHNDVAILTLSEPVPFTREIQPICL----PTSPSQQSRSYSGQVATVAGWGSLRENGPQ 543

  Fly   188 IPRVLKHSVGDRIDREL-----CTLKFQQQ----VDESQICVHTETSHACKGDSGGPFSAKILYG 243
             |.:|:     ::|..:     |..|:.:.    :.||.||.......:|.||||||.  .|..|
  Fly   544 -PSILQ-----KVDIPIWTNAECARKYGRAAPGGIIESMICAGQAAKDSCSGDSGGPM--VINDG 600

  Fly   244 GTYRTFQFGIIIFGLSSCAGL--SVCTNVTFYMDWIW 278
            |.|.  |.||:.:|:....|.  .|.|.||..:.||:
  Fly   601 GRYT--QVGIVSWGIGCGKGQYPGVYTRVTSLLPWIY 635

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	74/249 (30%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	74/249 (30%)
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829
		Tryp_SPc	399..634	CDD:214473	76/262 (29%)
		Tryp_SPc	400..637	CDD:238113	78/264 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010