DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14227 and CLIPB3

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	XP_307750.3	Gene:	CLIPB3 / 3290783	VectorBaseID:	AGAP003249	Length:	365	Species:	Anopheles gambiae

Alignment Length:	259	Identity:	80/259 - (30%)
Similarity:	120/259 - (46%)	Gaps:	45/259 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 TDIQANPWIVSVIVNGKA------KCSGSLINHRFVLTAAHCV--FREAMQVH---LGDFDAWNP 104
            |.|...|| .::|...|.      .|.|||||.|:::|||||:  .....:||   ||::|
Mosquito   119 TQIDEFPW-TALIEFQKPDGSFGFHCGGSLINDRYIVTAAHCIKSIPRGWKVHRVRLGEWD---- 178

  Fly   105 GQNCSSGARLSNAYC------VRIDKKIVHAGFG-KIQAQQYDIGLLRMQHAVQYSDFVRPICL- 161
               .:|.....|.:|      :.|::.:||.|:. |.|:...||.|:|....|.||..||||||
Mosquito   179 ---LTSANDCQNEFCSDAPIDLDIEQIVVHTGYDTKDQSNANDIALIRFTRPVNYSQTVRPICLP 240

  Fly   162 ----LINEPVAAIDRFQLTVWGTTAEDFRSIPRVLKHSVGDRIDRELCTLKFQQ---QVDESQIC 219
                |.|...|.:..: ...||.| |...:..:.||..:..:..:| |...:|:   .:.::.:|
Mosquito   241 LSSSLRNRNHAGMPAY-AAGWGKT-ESATASEKKLKVEMNIKSLQE-CAPVYQRGGILLKKTHMC 302

  Fly   220 V-HTETSHACKGDSGGPFSAKILYGGTYRTFQFGIIIFGLSSCA--GL-SVCTNVTFYMDWIWD 279
            . .......|.||||||...::  .|::  :..|::.||...|.  |: .|.|||..|:|||.|
Mosquito   303 AGGVRGKDTCSGDSGGPLMRQM--SGSW--YLIGVVSFGPQKCGAPGVPGVYTNVAEYVDWIKD 362

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	75/249 (30%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	75/249 (30%)
CLIPB3	XP_307750.3	CLIP	37..89	CDD:288855
		Tryp_SPc	112..360	CDD:214473	77/255 (30%)
		Tryp_SPc	113..363	CDD:238113	80/259 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910