DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14227 and Tmprss11b

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_795998.2	Gene:	Tmprss11b / 319875	MGIID:	2442893	Length:	416	Species:	Mus musculus

Alignment Length:	276	Identity:	80/276 - (28%)
Similarity:	126/276 - (45%)	Gaps:	52/276 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LDAE------CGRSLPTNAKLTWWNYFDSSTDIQAN-PWIVSVIVNGKAKCSGSLINHRFVLTAA 84
            :|||      |||....:|  |:......||..:.. ||..|:.||||..|..|||..||:||||
Mouse   162 VDAEKIINNRCGRRPRMSA--TYDRITGGSTAHKGEWPWQASLRVNGKHYCGASLIGERFLLTAA 224

  Fly    85 HCVFREAMQVHLGDFDAWNPGQN--CSSGARLSNAYCVR-IDKKIVHAGFGKIQAQQYDIGLLRM 146
            ||            |...|..:|  .|.|.|::.||... :.:.|:|..:.|.:... |:.::::
Mouse   225 HC------------FQGTNNPKNLTVSFGTRVTPAYMQHSVQEIIIHEDYVKGEHHD-DVAVIKL 276

  Fly   147 QHAVQYSDFVRPICL----LINEPVAAIDRFQLTVWGTTAEDFRSIPRVLKHSVGDRIDRELCTL 207
            ...|.:::.|..:||    .|..|...:   .:|.||:.:.:.:| |.:|:.:....||...|..
Mouse   277 TEKVSFNNDVHRVCLPESTQIFPPGEGV---VVTGWGSFSYNGKS-PLLLQKASIKIIDTNTCNS 337

  Fly   208 K--FQQQVDESQICV-HTETS-HACKGDSGGPF----SAKILYGGTYRTFQFGIIIFGLSSCAGL 264
            :  :..::.::.:|. :.|.| .||:||||||.    |..|.|       ..||:.:| ..|..:
Mouse   338 EEAYGGRIVDTMLCAGYLEGSIDACQGDSGGPLVHPNSRDIWY-------LVGIVSWG-HECGRV 394

  Fly   265 S---VCTNVTFYMDWI 277
            :   |...||.|.:||
Mouse   395 NKPGVYMRVTSYRNWI 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	68/237 (29%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	68/237 (29%)
Tmprss11b	NP_795998.2	SEA	46..140	CDD:279699
		Tryp_SPc	184..410	CDD:214473	70/250 (28%)
		Tryp_SPc	185..413	CDD:238113	72/251 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910