DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14227 and Klkb1

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_036857.2	Gene:	Klkb1 / 25048	RGDID:	67382	Length:	638	Species:	Rattus norvegicus

Alignment Length:	262	Identity:	75/262 - (28%)
Similarity:	114/262 - (43%)	Gaps:	48/262 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 TNAKLTWWNYFDSSTDIQANPWIVSV---IVNGKAKCSGSLINHRFVLTAAHCVFREAMQVHLGD 98
            ||:.|..|            ||.||:   :|:....|.||:|..:::||||||
  Rat   395 TNSSLGEW------------PWQVSLQVKLVSQNHMCGGSIIGRQWILTAAHC------------ 435

  Fly    99 F------DAWNPGQNCSSGARLSN-AYCVRIDKKIVHAGFGKIQAQQYDIGLLRMQHAVQYSDFV 156
            |      |.|.......:.:.::| .....|.:.|:|..: |:....|||.|:::|..:.|::|.
  Rat   436 FDGIPYPDVWRIYGGILNLSEITNKTPFSSIKELIIHQKY-KMSEGSYDIALIKLQTPLNYTEFQ 499

  Fly   157 RPICLLINEPVAAI-DRFQLTVWGTTAEDFRSIPRVLKHSVGDRIDRELCTLKFQQQVDESQ-IC 219
            :||||........| ....:|.||.|.|...: ..:|:.:....:..|.|..|::..|...| ||
  Rat   500 KPICLPSKADTNTIYTNCWVTGWGYTKERGET-QNILQKATIPLVPNEECQKKYRDYVITKQMIC 563

  Fly   220 VHTETS--HACKGDSGGPFSAKILYGGTYRTFQFGIIIFGLSSCAGL---SVCTNVTFYMDWIWD 279
            ...:..  .|||||||||...|  :.|.::.  .||..:| ..||..   .|.|.|..|:|||.:
  Rat   564 AGYKEGGIDACKGDSGGPLVCK--HSGRWQL--VGITSWG-EGCARKEQPGVYTKVAEYIDWILE 623

  Fly   280 AL 281
            .:
  Rat   624 KI 625

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	69/236 (29%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	69/236 (29%)
Klkb1	NP_036857.2	APPLE	21..104	CDD:128519
		APPLE	111..194	CDD:128519
		APPLE	201..284	CDD:128519
		APPLE	292..375	CDD:128519
		Tryp_SPc	390..621	CDD:214473	73/256 (29%)
		Tryp_SPc	391..621	CDD:238113	73/256 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910