DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14227 and F9

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_113728.1	Gene:	F9 / 24946	RGDID:	2589	Length:	462	Species:	Rattus norvegicus

Alignment Length:	244	Identity:	65/244 - (26%)
Similarity:	102/244 - (41%)	Gaps:	51/244 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 PWIVSVIVNG--KAKCSGSLINHRFVLTAAHCVFREAMQVHLGDFDAWNPGQNCSSGARLSNAYC 119
            ||  .||:||  :|.|.|::||.::::|||||:               .||......|...|
  Rat   240 PW--QVILNGEIEAFCGGAIINEKWIVTAAHCL---------------KPGDKIEVVAGEHN--- 284

  Fly   120 VRIDKK------------IVHAGF-GKIQAQQYDIGLLRMQHAVQYSDFVRPICLLINEPVAAID 171
              ||:|            |.|..: ..|....:||.||.:...:..:.:|.|||:...|......
  Rat   285 --IDEKEDTEQRRNVIRTIPHHQYNATINKYSHDIALLELDKPLILNSYVTPICVANKEYTNIFL 347

  Fly   172 RF---QLTVWGTTAEDFRSIPRVLKHSVGDRIDRELCTLKFQQQVDESQICV--HTETSHACKGD 231
            :|   .::.||......|. ..:|::.....:||..|....:..:..:..|.  ......:|:||
  Rat   348 KFGSGYVSGWGKVFNKGRQ-ASILQYLRVPLVDRATCLRSTKFSIYNNMFCAGYREGGKDSCEGD 411

  Fly   232 SGGPFSAKILYGGTYRTFQFGIIIFGLSSCA---GLSVCTNVTFYMDWI 277
            ||||...::  .||  :|..|||.:| ..||   ...:.|.|:.|::||
  Rat   412 SGGPHVTEV--EGT--SFLTGIISWG-EECAMKGKYGIYTKVSRYVNWI 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	63/242 (26%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	63/242 (26%)
F9	NP_113728.1	GLA	21..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	127..163	CDD:291342
		Tryp_SPc	227..455	CDD:214473	63/242 (26%)
		Tryp_SPc	228..458	CDD:238113	65/244 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910