DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14227 and Mst1

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	XP_038936729.1	Gene:	Mst1 / 24566	RGDID:	3114	Length:	747	Species:	Rattus norvegicus

Alignment Length:	274	Identity:	70/274 - (25%)
Similarity:	116/274 - (42%)	Gaps:	66/274 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ECGRSLPTNAKLTWWNYFDSSTDIQA-------NPWIVSV-IVNGKAKCSGSLINHRFVLTAAHC 86
            :||:.:            |.|..::.       :||.||: ...|:..|.|||:..::||||..|
  Rat   507 KCGKRV------------DQSNRLRVVGGHPGNSPWTVSLRNRQGQHFCGGSLVKEQWVLTARQC 559

  Fly    87 VFREAMQVH--LGDFDAW--NPGQNCSSGARLSNAYCVRIDKKIVHAGFGKIQAQQYDIGLLRMQ 147
            ::    ..|  |..::.|  ...||...|.  :|...|.:.|.:.    |...:|   :.||:::
  Rat   560 IW----SCHDPLTGYEVWLGTINQNPQPGE--ANLQRVSVAKTVC----GPAGSQ---LVLLKLE 611

  Fly   148 HAVQYSDFVRPICLLINEPVAAI-DRFQLTVWGTTAEDFRS-IPRVLKHSVGDRIDRELCTLKFQ 210
            ..|..:..|..|||...:.|... ...::..||.:.....| :..|.|..|   |..:.|.:|::
  Rat   612 RPVILNHHVARICLPPEQYVVPPGTNCEIAGWGESKGTSNSTVLHVAKMKV---ISSQECNVKYR 673

  Fly   211 QQVDESQICVHTE----TSHACKGDSGGPFSAK-----ILYGGTYRTFQFGIIIFGLSSCA---G 263
            ::|.||:||  ||    .:.||:||.|||.:..     :|.|          :|.....||   .
  Rat   674 RRVQESEIC--TEGLLAPTGACEGDYGGPLACYTHDCWVLQG----------LIIPNRVCARPRW 726

  Fly   264 LSVCTNVTFYMDWI 277
            .::.|.|:.::|||
  Rat   727 PAIFTRVSVFVDWI 740

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	64/238 (27%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	64/238 (27%)
Mst1	XP_038936729.1	PAN_1	32..111	CDD:394981
		KR	116..196	CDD:214527
		KR	199..276	CDD:214527
		KR	321..403	CDD:214527
		KR	408..490	CDD:214527
		Tryp_SPc	520..743	CDD:238113	66/249 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336739
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930