DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14227 and Hgf

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	NP_058713.1	Gene:	Hgf / 24446	RGDID:	2794	Length:	728	Species:	Rattus norvegicus

Alignment Length:	245	Identity:	62/245 - (25%)
Similarity:	97/245 - (39%)	Gaps:	58/245 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 WIVSVIVNGKAKCSGSLINHRFVLTAAHCVFREAMQVHLGDFDAWNPGQNCSSGARLSNAYCVRI 122
            |:||:....|..|.||||...:||||..|.  .|....|.|::||....:............:.|
  Rat   508 WMVSLKYRNKHICGGSLIKESWVLTARQCF--PARNKDLKDYEAWLGIHDVHERGEEKRKQILNI 570

  Fly   123 DKKIVHAGFGKIQAQQYDIGLLRMQHAVQYSDFVRPI------CLLINEPVAAIDRFQLTVWGTT 181
             .::|:...|.      |:.||::.......:||..|      |.:..:...:|     ..||.|
  Rat   571 -SQLVYGPEGS------DLVLLKLARPAILDNFVSTIDLPSYGCTIPEKTTCSI-----YGWGYT 623

  Fly   182 ----AEDFRSIPRVLKHSVGDRIDRELCTLKFQQQV--DESQICVHTET--SHACKGDSGGPFSA 238
                |:....:..:  :.:|:    |.|:...|.:|  :||::|...|.  |..|:||.|||...
  Rat   624 GLINADGLLRVAHL--YIMGN----EKCSQHHQGKVTLNESELCAGAEKIGSGPCEGDYGGPLIC 682

  Fly   239 K------ILYGGTYRTFQFGIIIFGLSSCA-----GLSVCTNVTFYMDWI 277
            :      :|          |:|:.| ..||     |:.|  .|.:|..||
  Rat   683 EQHKMRMVL----------GVIVPG-RGCAIPNRPGIFV--RVAYYAKWI 719

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	60/243 (25%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	60/243 (25%)
Hgf	NP_058713.1	PAN_APPLE	41..123	CDD:238074
		KR	127..209	CDD:214527
		KR	211..289	CDD:214527
		KR	305..385	CDD:214527
		KR	389..471	CDD:238056
		Tryp_SPc	495..719	CDD:214473	60/243 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336717
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930