DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14227 and Tmprss13

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	XP_006510195.1	Gene:	Tmprss13 / 214531	MGIID:	2682935	Length:	561	Species:	Mus musculus

Alignment Length:	235	Identity:	62/235 - (26%)
Similarity:	100/235 - (42%)	Gaps:	30/235 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    57 PWIVSVIVNGKAKCSGSLINHRFVLTAAHCVF--REAMQVHLGDFDAWNPGQNCSSGARLSNAYC 119
            ||.||:.......|.|:||:.::|||||||.|  ||.:      .:.|......|:..:|..|
Mouse   332 PWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKL------LEGWKVYAGTSNLHQLPEA-- 388

  Fly   120 VRIDKKIVHAGFGKIQAQQYDIGLLRMQHAVQYSDFVRPICLLINEPVAAIDRFQLTVW----GT 180
            ..|.:.|::..:...| ..|||.|:|:...:..|..:.|.||.::.....::.   |.|    |.
Mouse   389 ASISQIIINGNYTDEQ-DDYDIALIRLSKPLTLSAHIHPACLPMHGQTFGLNE---TCWITGFGK 449

  Fly   181 TAEDFRSIPRVLKHSVGDRIDRELCT--LKFQQQVDESQICVHTETS--HACKGDSGGPFSAKIL 241
            |.|........|:....:.||.:.|.  |.:...:....:|......  .:|:||||||    ::
Mouse   450 TKETDEKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGP----LV 510

  Fly   242 YGGTYRTFQFGIIIFGLSSCAGLS---VCTNVTFYMDWIW 278
            .....|.:..|:..:| :.|...:   |.|.||..:.||:
Mouse   511 CEQNNRWYLAGVTSWG-TGCGQKNKPGVYTKVTEVLPWIY 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	60/232 (26%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	60/232 (26%)
Tmprss13	XP_006510195.1	PHA03378	<6..>122	CDD:223065
		LDLa	<204..220	CDD:238060
		SRCR_2	225..314	CDD:373897
		Tryp_SPc	319..548	CDD:214473	60/232 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910