DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14227 and tmprss15

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	XP_001919639.2	Gene:	tmprss15 / 100148042	ZFINID:	ZDB-GENE-091204-83	Length:	990	Species:	Danio rerio

Alignment Length:	281	Identity:	72/281 - (25%)
Similarity:	120/281 - (42%)	Gaps:	62/281 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 CG-RSLPTNAKLTWWNYFDSSTDIQ--------------ANPWIVSVIVNGKAKCSGSLINHRFV 80
            || |.:|:.:|:.      ..||.:              |.||:||:...|...|..:||:..::
Zfish   725 CGVRKVPSKSKII------EETDGKKEGRVVGGQDAQRGAWPWMVSLQWLGGHACGATLIDREWL 783

  Fly    81 LTAAHCVFREAMQVH-----LG---DFDAWNPGQNCSSGARLSNAYCVRIDKKIVHAGFGKIQAQ 137
            :||||||:...:|:.     ||   .|:..||.:...|           :|:.|:|..:.| :.:
Zfish   784 ITAAHCVYGRNVQLSNWAAVLGLHAQFETINPNKQVFS-----------VDQVIMHKHYNK-RTK 836

  Fly   138 QYDIGLLRMQHAVQYSDFVRPICLLINEPVAAIDRFQ---LTVWGTTAEDFRSIPRVLKHSVGDR 199
            :.|..|:.::..|.|:|:|:||||  .:|.|..:..:   :..||..:|...... ||:.:|...
Zfish   837 ESDFALMHLKTPVSYTDYVQPICL--PDPGAHFEEGRKCFIAGWGLLSESGLKAD-VLQQAVVPL 898

  Fly   200 IDRELCTLKF-QQQVDESQICV-HTETS-HACKGDSGGPFSAK-----ILYGGTYRTFQFGIIIF 256
            :....|.... :....|..:|. :.|.. ..|:||||||...:     :|.|.|    .|||
Zfish   899 LSNTQCQEWLPEYNFTERMMCAGYAEGGVDTCQGDSGGPLMCEEEGHWVLVGAT----SFGI--- 956

  Fly   257 GLSSCAGLSVCTNVTFYMDWI 277
            |............|:.::||:
Zfish   957 GCGRPQRPGAYARVSQFVDWV 977

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	63/238 (26%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	63/238 (26%)
tmprss15	XP_001919639.2	SEA	19..>89	CDD:279699
		LDLa	142..175	CDD:238060
		CUB	183..288	CDD:238001
		MAM	302..457	CDD:279023
		MAM	302..457	CDD:99706
		CUB	477..586	CDD:238001
		LDLa	596..630	CDD:238060
		SRCR_2	653..728	CDD:295335	2/2 (100%)
		Tryp_SPc	747..977	CDD:214473	64/251 (25%)
		Tryp_SPc	748..980	CDD:238113	65/252 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910