DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14227 and LOC100004411

DIOPT Version :9

Sequence 1:	NP_608345.2	Gene:	CG14227 / 32978	FlyBaseID:	FBgn0031058	Length:	286	Species:	Drosophila melanogaster
Sequence 2:	XP_001343728.4	Gene:	LOC100004411 / 100004411	-ID:	-	Length:	494	Species:	Danio rerio

Alignment Length:	242	Identity:	68/242 - (28%)
Similarity:	112/242 - (46%)	Gaps:	38/242 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    56 NPWIVSVIVNGKAK---CSGSLINHRFVLTAAHCVFREAMQVHLGDFDAWNPGQNCSSGARLSNA 117
            :||  .|::..:.:   |.|||||.|:|:|||||:.:....:.:||:|...|.::...
Zfish   260 SPW--QVLLRREDEYGFCGGSLINQRWVITAAHCLQQTPHHITIGDYDKMRPDKDEQK------- 315

  Fly   118 YCVRIDKKIVHAGFGKIQAQQY----DIGLLRMQHAVQYSDFVRPICL----LINEPVAAIDRFQ 174
              :.::|.|.|..:     .:|    ||.||.:..||....|..|.||    |....:...::..
Zfish   316 --ITVEKIIPHPHY-----HEYTFDSDIALLYLSSAVTLGPFASPACLPDANLAERLMKPGEQGL 373

  Fly   175 LTVWGTTAEDFRSIPRVLKHSVGDRIDRELCTLKFQQQVDESQICVH--TETSHACKGDSGGPFS 237
            ::.||:|....|| .|.|:......::::.|....:|.:.::..|..  .|...||.|||||||.
Zfish   374 VSGWGSTHYLQRS-SRFLRKVQLPVVEQKSCINSTEQIITDNMFCAGFLMEEMDACTGDSGGPFI 437

  Fly   238 AKILYGGTYRTFQFGIIIFGLSSCAG---LSVCTNVTFYMDWIWDAL 281
              :.|.||:  |..|::.:| ..||.   ..|.|.:..|:.||.:.:
Zfish   438 --VNYRGTW--FLTGVVSWG-ERCASQGKYGVYTRLGNYLSWIQEEM 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:214473	66/235 (28%)
CG14227	NP_608345.2	Tryp_SPc	57..277	CDD:238113	66/235 (28%)
LOC100004411	XP_001343728.4	GLA	22..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	128..164	CDD:291342
		Tryp_SPc	248..475	CDD:214473	66/236 (28%)
		Tryp_SPc	249..477	CDD:238113	68/238 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910