DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubqn and RAD23

DIOPT Version :9

Sequence 1:	NP_001285457.1	Gene:	Ubqn / 32977	FlyBaseID:	FBgn0031057	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	NP_010877.3	Gene:	RAD23 / 856674	SGDID:	S000000763	Length:	398	Species:	Saccharomyces cerevisiae

Alignment Length:	430	Identity:	93/430 - (21%)
Similarity:	156/430 - (36%)	Gaps:	98/430 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 KDKKTVEVDEDSGIKDFKILVAQKFEAEPEQLVLIFAGKIMKDTDTLQMHNIKDNLTVHLVI--K 79
            |:|..::::..:.|.:.|..:||....|..|:.||::||:::|:.|:....:||...|..::  |
Yeast    11 KEKVPLDLEPSNTILETKTKLAQSISCEESQIKLIYSGKVLQDSKTVSECGLKDGDQVVFMVSQK 75

  Fly    80 APTRNN-EQPARQPADVRQTPFGLNQFGGLAGMEALGAGSNTFMDLQARMQNELLNNGDMLRSLM 143
            ..|:.. .:|...| :...||...|........:|..|.:.|..:                   .
Yeast    76 KSTKTKVTEPPIAP-ESATTPGRENSTEASPSTDASAAPAATAPE-------------------G 120

  Fly   144 DNPMVQQMMNNPDTMRQLITSNPQMHDLMQRNPEISHMLNNPDLLRQTMELARNPSMLQELMRSH 208
            ..|..:|   ...|.|....|.|......:||..|..::   ::..|..|:.|   .|:....:.
Yeast   121 SQPQEEQ---TATTERTESASTPGFVVGTERNETIERIM---EMGYQREEVER---ALRAAFNNP 176

  Fly   209 DRAMSNLESVPGGYSALQRIYRDIQEPMMNAATESFGRNPFAGLVDGGGSGAGNNPQQGTENRNP 273
            |||:..|         |..|..::::|.....|.:....|         |.|....:|..|:...
Yeast   177 DRAVEYL---------LMGIPENLRQPEPQQQTAAAAEQP---------STAATTAEQPAEDDLF 223

  Fly   274 LPNPWGG-ANSGTNGTVGGSGAGNPTGDLPPNNV-LNTPAMRSLLQQMADNPAMMQNLLNAPYTR 336
            .....|| |:||..||.||:......|  ||.:: |....:.||.|.::.||..:
Yeast   224 AQAAQGGNASSGALGTTGGATDAAQGG--PPGSIGLTVEDLLSLRQVVSGNPEAL---------- 276

  Fly   337 SMMESMSQDPDMAARLLSSSPLMSNNPALQEQVRQMMPQFMAQMQNPEV-MNMLTNPDAMNAILQ 400
                               :||:.|..|...|:|:.:      |.|||| ::||        :..
Yeast   277 -------------------APLLENISARYPQLREHI------MANPEVFVSML--------LEA 308

  Fly   401 IQQGMEQLRSAAPGLVGTLGIPPPPPGAGTGTNPASGDGS 440
            :...|:.:...|..:|....|......|..|.....|:||
Yeast   309 VGDNMQDVMEGADDMVEGEDIEVTGEAAAAGLGQGEGEGS 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubqn	NP_001285457.1	UBQ	9..79	CDD:214563	17/63 (27%)
		hPLIC_N	9..79	CDD:176403	17/63 (27%)
		STI1	322..368	CDD:128966	6/45 (13%)
		UBA_PLICs	501..537	CDD:270582
RAD23	NP_010877.3	rad23	2..398	CDD:273167	93/430 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900