DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubqn and AT2G17190

DIOPT Version :9

Sequence 1:	NP_001285457.1	Gene:	Ubqn / 32977	FlyBaseID:	FBgn0031057	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	NP_565407.1	Gene:	AT2G17190 / 816224	AraportID:	AT2G17190	Length:	538	Species:	Arabidopsis thaliana

Alignment Length:	596	Identity:	213/596 - (35%)
Similarity:	299/596 - (50%)	Gaps:	124/596 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 AEGGSKRINVVVKTPKDKKTVEVDEDSGIKDFKILVAQKFEAEPEQLVLIFAGKIMKDTDTLQMH 66
            |||.:..:||.... ..|.:|....||.::.||.|:||..:....|..||:.|:|:||..||..:
plant    13 AEGVAVAVNVRCSN-GTKFSVTTSLDSTVESFKELIAQNSDVPANQQRLIYKGRILKDDQTLLSY 76

  Fly    67 NIKDNLTVHLV-------IKAPTRN--NEQPARQPA---DVRQTPFGLNQFGGLAGMEALGAGS- 118
            .::.:.|||:|       ..||..|  |:..|.|..   |......|.:.|.|| |...||.|:
plant    77 GLQADHTVHMVRGFVPSSPSAPAANAGNQTTAPQAVGSNDSSNLGGGESLFPGL-GFNPLGGGNA 140

  Fly   119 ------NTFMDLQARMQNELLNNGDMLRSLMDNPMVQQMMNNPDTMRQLITSNPQMHDLMQRNPE 177
                  :...||: :.|.:|..|.:|:|.:|:.|.:|.:||||:.||.:|.:||||.:|:.||||
plant   141 MAGLFGSGLPDLE-QAQQQLAQNPNMIREMMNTPAIQNLMNNPEFMRSMIMNNPQMRELVDRNPE 204

  Fly   178 ISHMLNNPDLLRQTMELARNPSMLQELMRSHDRAMSNLESVPGGYSALQRIYRDIQEPMMNAAT- 241
            :.|:||:|.:||||:|.||||.:::|:||:.||||||:||:|.|::.|:|:|.::|||:|||.|
plant   205 LGHVLNDPSILRQTLEAARNPELMREMMRNTDRAMSNIESMPEGFNMLRRMYENVQEPLMNATTM 269

  Fly   242 -ESFGR----NPFAGL-----VDGGGSGAGN-----NPQQGTENRNPLPNPWGG----------A 281
             |:.|.    ||||.|     |...||...|     |.:.||.|.||||||||.          .
plant   270 SENAGNNTSSNPFAALLGNQGVTTQGSDTSNNISAPNAETGTPNANPLPNPWGATAGQTTAPGRT 334

  Fly   282 NSGTNGTVGGSGAGNPTGDLPPNNVLNTPAMRSLLQQMADNPAMMQNLLNAPYTRSMMESMSQDP 346
            |:|..| :||.|.....|.|..::.|......|.|.|:..||||.|          ||:|:..:|
plant   335 NAGLGG-LGGLGGLGGLGMLGADSPLGATPDASQLSQILQNPAMSQ----------MMQSVLSNP 388

  Fly   347 DMAARLLSSSPLMSNNPALQEQVRQMMPQFMAQMQNPEVMNMLTNPDAMNAILQIQQGM-EQLRS 410
            ..      .:.|||.||.|:..: .|.||....||||:.:...::|:.|..::.:||.: .|.|:
plant   389 QY------MNQLMSLNPQLRSML-DMNPQLREMMQNPDFLRQFSSPEMMQQMMSLQQSLFSQNRN 446

  Fly   411 AAPGLVGTLGIPPPPPGAGTGTNPASG-------DGSGGNSGASTNNVSPSSGLNAGTGTPNLAP 468
                   |.|..|...||.|||....|       .||.|..|.|            ||..||:
plant   447 -------TAGQDPTQTGAATGTANNGGLDLLMNMFGSLGAGGLS------------GTNQPNV-- 490

  Fly   469 GGGPNAQLFNDFMMRMLNGMSNNADNTQPPEVRYQSQLEQLNAMGFVNRDANLQALIATFGDINA 533
                                        |||.|:.:||:||..|||.:|..|::||:||.|::||
plant   491 ----------------------------PPEERFATQLQQLQEMGFYDRAENIRALLATNGNVNA 527

  Fly   534 AVERLL-SLNQ 543
            |||||| |:.|
plant   528 AVERLLGSIGQ 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubqn	NP_001285457.1	UBQ	9..79	CDD:214563	24/76 (32%)
		hPLIC_N	9..79	CDD:176403	24/76 (32%)
		STI1	322..368	CDD:128966	15/45 (33%)
		UBA_PLICs	501..537	CDD:270582	19/35 (54%)
AT2G17190	NP_565407.1	Ubl_Dsk2p_like	18..90	CDD:340523	24/72 (33%)
		STI1	367..402	CDD:128966	16/50 (32%)
		UBA_PLICs	495..534	CDD:270582	22/38 (58%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	224	1.000	Domainoid score	I694
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	287	1.000	Inparanoid score	I847
OMA	1	1.010	-	-		QHG54270
OrthoDB	1	1.010	-	-		D1553668at2759
OrthoFinder	1	1.000	-	-		FOG0001496
OrthoInspector	1	1.000	-	-		otm2477
orthoMCL	1	0.900	-	-		OOG6_100933
Panther	1	1.100	-	-	LDO	PTHR10677
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X761
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	14	13.840