DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubqn and RAD23A

DIOPT Version :9

Sequence 1:	NP_001285457.1	Gene:	Ubqn / 32977	FlyBaseID:	FBgn0031057	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	XP_024307399.1	Gene:	RAD23A / 5886	HGNCID:	9812	Length:	382	Species:	Homo sapiens

Alignment Length:	386	Identity:	77/386 - (19%)
Similarity:	131/386 - (33%)	Gaps:	102/386 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 INVVVKTPKDKK-TVEVDEDSGIKDFKILVAQKFEAEPEQ-------LVLIFAGKIMKDTDTLQM 65
            :.:.:||.:.:. .:.::.|..:|..|    :|.|||..:       ..||:||||:.|...::.
Human     3 VTITLKTLQQQTFKIRMEPDETVKVLK----EKIEAEKGRDAFPVAGQKLIYAGKILSDDVPIRD 63

  Fly    66 HNIKD-NLTVHLVIK---------------------------APT----------RNNEQPARQ- 91
            :.|.: |..|.:|.|                           |||          |.::.|:.:
Human    64 YRIDEKNFVVVMVTKTKAGQGTSAPPEASPTAAPESSTSFPPAPTSGMSHPPPAAREDKSPSEES 128

  Fly    92 -PADVRQTPFGLNQFGGLAGMEALGAGSNTFMDLQARMQNELLNNGDMLRSLMDNPMVQQMMNNP 155
             |....::..|.....|.:|.|...|.:.........|..|:::.|.....::  ..::...|||
Human   129 APTTSPESVSGSVPSSGSSGREEDAASTLVTGSEYETMLTEIMSMGYERERVV--AALRASYNNP 191

  Fly   156 D-TMRQLITSNPQMHDLMQRNPEISHMLNNPDLLRQTMELARNPSMLQ------ELMRSHDRA-- 211
            . .:..|:|..|...:....:.:.|.:...|  ..:....|...|.||      ...||..|:
Human   192 HRAVEYLLTGIPGSPEPEHGSVQESQVSEQP--ATEAGGCAHAASALQVPDSHYTPPRSAPRSPA 254

  Fly   212 ---------MSNLE--SVPGGYSALQRIYRDIQEPMMNAATESFGRNPFAGLVDGGGSGAG---- 261
                     .|..|  .||.|.:.:..          :||.:|  ..|.|.......:|.|
Human   255 WCLTAPLPTTSRREPPGVPAGPAPVPE----------HAAGDS--AEPCAAARPAPAAGPGEPSA 307

  Fly   262 ---NNPQQGTENRNPLPNPWGGANSGTNGTVGGSGA----GNPTGDLPPNNVLNTPAMRSL 315
               |.|..|..:.:....|||   :|.:...||.|.    |.|..:|.|.:.....:.|.:
Human   308 FTANQPAPGAVHPDAERAPWG---AGGHLRCGGGGGRHRRGGPADELHPGDAAGERSYREV 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubqn	NP_001285457.1	UBQ	9..79	CDD:214563	20/78 (26%)
		hPLIC_N	9..79	CDD:176403	20/78 (26%)
		STI1	322..368	CDD:128966
		UBA_PLICs	501..537	CDD:270582
RAD23A	XP_024307399.1	UBQ	3..>228	CDD:333228	43/232 (19%)
RAD23A	XP_024307399.1	DNA_pol3_gamma3	<81..378	CDD:331207	56/304 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900