DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ubqn and Ubl4a

DIOPT Version :9

Sequence 1:	NP_001285457.1	Gene:	Ubqn / 32977	FlyBaseID:	FBgn0031057	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	NP_663380.1	Gene:	Ubl4a / 27643	MGIID:	95049	Length:	157	Species:	Mus musculus

Alignment Length:	235	Identity:	45/235 - (19%)
Similarity:	80/235 - (34%)	Gaps:	84/235 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 INVVVKTPKDKK-TVEVDEDSGIKDFKILVAQKFEAEPEQLVLIFAGKIMKDTDTLQMHNIKDNL 72
            :.:.||..:.:: :::|.||..:...|.||:.|......|..|:|.||.:.|...|..:||..|.
Mouse     1 MQLTVKALQGRECSLQVAEDELVSTLKHLVSDKLNVPVRQQRLLFKGKALADEKRLSDYNIGPNS 65

  Fly    73 TVHLVIKAPTRNNEQPARQPADVRQTPFGLNQFGGLAGMEALGAGSNTFMDLQARMQNELLNNGD 137
            .::||:|.                                               ::..||..|.
Mouse    66 KLNLVVKP-----------------------------------------------LEKVLLEEGS 83

  Fly   138 MLRSLMDNPMVQQMMNNPDTMRQLITSNPQMHDLMQRNPEISHMLNNPDLLRQTMELARNPSMLQ 202
            ..| |:|:|..        .:.|||:.                      :|.:...:|....:|:
Mouse    84 AHR-LVDSPAT--------PIWQLISK----------------------VLARHFSVADASRVLE 117

  Fly   203 ELMRSHDRAMSNLESVPGGYSALQRIYRDIQEPMMNAATE 242
            :|.|.:||::|.|.     ...::|:......|.:..|.|
Mouse   118 QLQRDYDRSLSRLT-----LDDIERLASRFLHPEVTEAME 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubqn	NP_001285457.1	UBQ	9..79	CDD:214563	21/70 (30%)
		hPLIC_N	9..79	CDD:176403	21/70 (30%)
		STI1	322..368	CDD:128966
		UBA_PLICs	501..537	CDD:270582
Ubl4a	NP_663380.1	Ubl_UBL4A_like	1..72	CDD:340505	21/70 (30%)
		Tugs	96..142	CDD:375372	13/72 (18%)
		Required and sufficient for interaction with BAG6. /evidence=ECO:0000250\|UniProtKB:P11441	96..138		12/68 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900