DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ubqn and SPBC1E8.02

DIOPT Version :9

Sequence 1:	NP_001285457.1	Gene:	Ubqn / 32977	FlyBaseID:	FBgn0031057	Length:	547	Species:	Drosophila melanogaster
Sequence 2:	NP_001342703.1	Gene:	SPBC1E8.02 / 2540657	PomBaseID:	SPBC1E8.02	Length:	603	Species:	Schizosaccharomyces pombe

Alignment Length:	433	Identity:	91/433 - (21%)
Similarity:	161/433 - (37%)	Gaps:	145/433 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 VVKTPKDKKTVEVDEDSGIKDFKILVAQKFEAEPEQLVLIFAGKIMKDTDTLQ--MHNIKDNLTV 74
            :.:.|:.|..:|:.|         |:|..|||..::|.||.||:::::...|:  :|:..|.:|.
pombe    17 IFQVPRTKTVLELKE---------LIAVTFEAPADRLKLIHAGRVLRNETPLEEILHDATDLVTF 72

  Fly    75 HLVI------------------------------KAPT-----RNNEQPARQPADVR--QTPFGL 102
            ||||                              ..||     .|.|:.:|:....|  ||   .
pombe    73 HLVIAVFNSTSTTLPSATSSSVPQSRTSELSSTNSIPTPRITSLNPEELSRRERAQRLLQT---Y 134

  Fly   103 NQFGGLAGMEALGAGSNTFMDLQARMQNELLNNGDMLRSLMDNPMVQQMMNNPDTMRQLITS--N 165
            |.|.|    ..||.       |...:..||.::|..|.:...:..|.:.::|.      ::|  :
pombe   135 NSFHG----SGLGG-------LFPNIHRELESHGFSLPTHEQSSPVAESLDNS------VSSALS 182

  Fly   166 PQMHDLMQRNPEISHMLNNPDLLRQTMELARNPSMLQELMRSHDRAMSNLES-VPGGYSALQRIY 229
            |.:..|.:||..|.|                      :.:::|:.|..:||: .||..|:.....
pombe   183 PHLETLRRRNLSIHH----------------------QHIQAHEMAQESLETRNPGNISSSSAPL 225

  Fly   230 RDIQEPMMNA----ATESFGRNPFAGLVDGGGSGAGNNPQQGTENRNPLPNPWGGANSGTNGTVG 290
            ...|.|.:::    |:.:...          ||.:|.||:......:||.||.......||  |.
pombe   226 ASDQSPTVSSNHIHASGNLAL----------GSNSGLNPRSPNSFSSPLDNPALHTVDSTN--VN 278

  Fly   291 GS-----------------------GAGNPT-GDLPPNNVLNTPAMRSLLQQMADNPAMMQNLLN 331
            ||                       ...||. ..:.|::..:.|:      .::.|||..:|
pombe   279 GSLSPLSNSSSINQVHQNETHGSTISVPNPNLSQMGPSHSSSVPS------NLSPNPAQNEN--- 334

  Fly   332 APYTRSMMESMSQDPDMAARLLSSSPLMSNNPALQEQVRQMMP 374
             |.|.| :.|::..| ..:.|.:|:...:::..:.:.|.|::|
pombe   335 -PSTTS-IPSINNQP-FPSGLSASNSNFASSSFIPQSVPQLLP 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ubqn	NP_001285457.1	UBQ	9..79	CDD:214563	22/98 (22%)
		hPLIC_N	9..79	CDD:176403	22/98 (22%)
		STI1	322..368	CDD:128966	11/45 (24%)
		UBA_PLICs	501..537	CDD:270582
SPBC1E8.02	NP_001342703.1	ubiquitin	6..76	CDD:306702	20/67 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5272
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10677
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000