Protein Alignment Ubqn and Ubqln1

DIOPT Version :10

• Sequence 1: NP_608344.1
• Gene: Ubqn / 32977
• FlyBaseID: FBgn0031057
• Length: 547
• Species: Drosophila melanogaster
• Sequence 2: NP_446199.2
• Gene: Ubqln1 / 114590
• RGDID: 620745
• Length: 582
• Species: Rattus norvegicus
• Alignment Length: 575
• Identity: 285/575 - (49%)
• Similarity: 377/575 - (65%)
• Gaps: 65/575 - (11%)

  Fly     7 KRINVVVKTPKDKKTVEVDEDSGIKDFKILVAQKFEAEPEQLVLIFAGKIMKDTDTLQMHNIKDN 71
            |.:.|.|||||:|:...|.|:|.::.||..::::|::..:||||||||||:||.|||..|.|.|.
  Rat    26 KIMKVTVKTPKEKEEFAVPENSSVQQFKEEISKRFKSHIDQLVLIFAGKILKDQDTLSQHGIHDG 90

  Fly    72 LTVHLVIKAPTRNNEQPARQ-----------PA--------DVRQTPFGLNQFGGLAGMEALGAG 117
            ||||||||...|..:..|:|           ||        ....:.|||...|||||:.:||..
  Rat    91 LTVHLVIKTQNRPQDNSAQQTNTTGNSVTSSPAPDSNPTSGPAANSSFGLGGLGGLAGLSSLGLN 155

  Fly   118 SNTFMDLQARMQNELLNNGDMLRSLMDNPMVQQMMNNPDTMRQLITSNPQMHDLMQRNPEISHML 182
            :..|.:||::||.:||:|.:|:..:|:||.||.|::|||.|||||.:||||..|:||||||||||
  Rat   156 TTNFSELQSQMQRQLLSNPEMMVQIMENPFVQSMLSNPDLMRQLIMANPQMQQLIQRNPEISHML 220

  Fly   183 NNPDLLRQTMELARNPSMLQELMRSHDRAMSNLESVPGGYSALQRIYRDIQEPMMNAATESFGRN 247
            ||||::|||:||||||:|:||:||:.|||:|||||:||||:||:|:|.||||||:|||.|.||.|
  Rat   221 NNPDIMRQTLELARNPAMMQEMMRNQDRALSNLESIPGGYNALRRMYTDIQEPMLNAAQEQFGGN 285

  Fly   248 PFAGLVDGGGSGAGNNPQQGTENRNPLPNPW----------GGANSGTNGTVGGSGAGNPT---- 298
            |||.||....|..|..|.: ||||:||||||          .|:...|..||..| |||.|
  Rat   286 PFASLVSSPSSAEGTQPSR-TENRDPLPNPWAPQTPQSSPASGSTGSTTNTVSTS-AGNATSTPA 348

  Fly   299 --GDLPPN-------NVLNTPAMRSLLQQMADNPAMMQNLLNAPYTRSMMESMSQDPDMAARLLS 354
              |...||       ::.|||.|:|||||:.:||.:|||:|:|||.||||:|:||:||:||:::.
  Rat   349 GQGTSGPNLVPGAGASMFNTPGMQSLLQQITENPQLMQNMLSAPYMRSMMQSLSQNPDLAAQMML 413

  Fly   355 SSPLMSNNPALQEQVRQMMPQFMAQMQNPEVMNMLTNPDAMNAILQIQQGMEQLRSAAPGLVGTL 419
            ::||.:.||.||||:||.:|.|:.|||||:.::.::||.||.|:||||||::.|.:.||||
  Rat   414 NNPLFAGNPQLQEQMRQQLPTFLQQMQNPDTLSAMSNPRAMQALLQIQQGLQTLATEAPGL---- 474

  Fly   420 GIPPPPPGAGTGTNPASGDGSGGNSGASTNNVSPSSGLNAGTGTPNLAPGGGPNAQLFNDFMMRM 484
             ||...||...|       .|||.:|.:..:.:|....|         |.||........|:.:|
  Rat   475 -IPGFTPGLAAG-------NSGGPAGTTAPSTAPGEDTN---------PQGGAAEPGHQQFIQQM 522

  Fly   485 LNGMSNNADNTQPPEVRYQSQLEQLNAMGFVNRDANLQALIATFGDINAAVERLL 539
            |..::......|.||||:|.|||||:||||:||:|||||||||.||||||:||||
  Rat   523 LQALAGVNPQLQSPEVRFQQQLEQLSAMGFLNREANLQALIATGGDINAAIERLL 577

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ubqn	NP_608344.1	Ubl_PLICs	7..79	CDD:340506	38/71 (54%)
		PABP-1234	<233..409	CDD:130689	98/198 (49%)
		UBA_PLICs	501..537	CDD:270582	28/35 (80%)
Ubqln1	NP_446199.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26		285/575 (50%)
		Ubl_PLICs	26..98	CDD:340506	38/71 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..136		5/33 (15%)
		Interaction with UBXN4. /evidence=ECO:0000250|UniProtKB:Q9UMX0	169..422		141/254 (56%)
		STI1	173..210	CDD:128966	20/36 (56%)
		STI1	203..247	CDD:450205	33/43 (77%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	285..365		31/81 (38%)
		STI1	384..416	CDD:128966	18/31 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	481..513		11/47 (23%)
		UBA_PLICs	539..578	CDD:270582	32/39 (82%)