DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment et and PTPRQ

DIOPT Version :9

Sequence 1:NP_001245761.1 Gene:et / 32975 FlyBaseID:FBgn0031055 Length:645 Species:Drosophila melanogaster
Sequence 2:XP_016874762.1 Gene:PTPRQ / 374462 HGNCID:9679 Length:2536 Species:Homo sapiens


Alignment Length:609 Identity:120/609 - (19%)
Similarity:208/609 - (34%) Gaps:160/609 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   118 LLNLKDFVCRDVVYYLRCTFSRME--NGNFENKTHYQLAMGRAKPIDCRKSEDE----------R 170
            ::|.|:.....::.|    :...|  ||...:.|.|.:.:...:.......::.          :
Human   796 IINYKNISSSSILLY----WDPPEYPNGKITHYTIYAMELDTNRAFQITTIDNSFLITGLKKYTK 856

  Fly   171 SRGKVECSVPIDPNSRAPEWRDFRLIMSDDLGNQS----KVLRLTQAEMEVLEW-PRGKHNMIQT 230
            .:.:|..|..:..:|.:.| .|..:..|:|....|    :|:.:|..|:. |:| |..|.|.|..
Human   857 YKMRVAASTHVGESSLSEE-NDIFVRTSEDEPESSPQDVEVIDVTADEIR-LKWSPPEKPNGIII 919

  Fly   231 PNQTCLEWNGPFIYPNRTFELNVQFRHSKLPNLSRNLTVSQMRAVSVFDQVCFGNPPEGNQLFYV 295
            ..:. |..|...:|...|...::         :.|||....:..:||.....||:..:.:.|..|
Human   920 AYEV-LYKNIDTLYMKNTSTTDI---------ILRNLRPHTLYNISVRSYTRFGHGNQVSSLLSV 974

  Fly   296 SLSRRLHGS-PWSERYP-----EFELTTNASLPARPPRFLANGFSHDRAKRELKVYWLPLDELEF 354
            ..|..:..| |.:..|.     |.||   :.||...|    ||.        ::.|.:.|.  ..
Human   975 RTSETVPDSAPENITYKNISSGEIEL---SFLPPSSP----NGI--------IQKYTIYLK--RS 1022

  Fly   355 NGAEQTYVASTRYGTKVATTQG-SMLAIFTDWDDTQPATVSVWSSNVVGRSLESSQLEVPRLSDI 418
            ||.|:..:.:|      :.||. .:|..:|.:      .:.|.:|.:.|..:.|:.:.:....|.
Human  1023 NGNEERTINTT------SLTQNIKVLKKYTQY------IIEVSASTLKGEGVRSAPISILTEEDA 1075

  Fly   419 RD---RRIYLESYNKTSSRLSWQGP-EELGNFTGYIVY-WCKLSSKVHDACDDSSSIETTYARET 478
            .|   :...::..:..:.:||||.| |..|....|.|| |            :.||::|....||
Human  1076 PDSPPQDFSVKQLSGVTVKLSWQPPLEPNGIILYYTVYVW------------NRSSLKTINVTET 1128

  Fly   479 AYNFSGIQGVIRMAVAANYSDGLTTGMRWWSGDS-------EVPE-----KPKILRYVEGTIALL 531
            :...|.:.      ....||..:|...|:..|.:       :.||     .||.:.|...:.:.:
Human  1129 SLELSDLD------YNVEYSAYVTASTRFGDGKTRSNIISFQTPEGAPSDPPKDVYYANLSSSSI 1187

  Fly   532 VL-----------------------GSLV------------------LAIQKLRQMADIRVELPV 555
            :|                       |:.:                  ..|.||...:.....|..
Human  1188 ILFWTPPSKPNGIIQYYSVYYRNTSGTFMQNFTLHEVTNDFDNMTVSTIIDKLTIFSYYTFWLTA 1252

  Fly   556 MSEEPTANPLGDVRLFYPANVPPEKFYGTVRKTVTFAEEEPTRWPEIELQEVPRPQPVPQADAYV 620
            .:.....|...|:...|.....||.|.|    .:|:.....|   .|.:..||..||     ..:
Human  1253 STSVGNGNKSSDIIEVYTDQDIPEGFVG----NLTYESISST---AINVSWVPPAQP-----NGL 1305

  Fly   621 TNQYVSMSAIGAPCGDGYIKPPPV 644
            ...|||:.....|   .:::||.|
Human  1306 VFYYVSLILQQTP---RHVRPPLV 1326



Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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