DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zw and G6PD3

DIOPT Version :9

Sequence 1:	NP_523411.1	Gene:	Zw / 32974	FlyBaseID:	FBgn0004057	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_173838.1	Gene:	G6PD3 / 839044	AraportID:	AT1G24280	Length:	599	Species:	Arabidopsis thaliana

Alignment Length:	492	Identity:	228/492 - (46%)
Similarity:	314/492 - (63%)	Gaps:	13/492 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LIIKSLKSPTMVCEGTHFDGKIPHTFVIFGASGDLAKKKIYPTLWWLYRDDLLPKPTKFCGYARS 77
            |.|.||::..:|.|....:.....:..:.|||||||||||:|.|:.||.:..||:.....|||||
plant    90 LTIPSLEADKVVAESDGGEQLSTVSITVVGASGDLAKKKIFPALFALYYEGCLPEHFTIFGYARS 154

  Fly    78 MLTVDSIKEQCLPYMKVQPHEQ----KKYEEFWALNEYVSGRYDGRTGFELLNQQLEIMENKNKA 138
            .:|...::......:..:..::    :|.|||.....|.||:||.:..|..|:::|:..|....:
plant   155 KMTDAELRVMVSKTLTCRIDKRANCGEKMEEFLKRCFYHSGQYDSQEHFVALDEKLKEHEGGRLS 219

  Fly   139 NRIFYLALPPSVFEEVTVNIKQICMSVCGWNRVIIEKPFGRDDASSQALSDHLAGLFQEDQLYRI 203
            ||:|||::||::|.:..........||.||.|||:|||||||..:|.||:..|....:|||::||
plant   220 NRLFYLSIPPNIFVDAVKCASSSASSVNGWTRVIVEKPFGRDSKTSAALTKSLKQYLEEDQIFRI 284

  Fly   204 DHYLGKEMVQNLMTIRFGNKILSSTWNRENIASVLITFKEPFGTQGRGGYFDEFGIIRDVMQNHL 268
            |||||||:|:||..:||.|.|....|:|:.|.:|...|.|.|||:|||||||.:|||||:|||||
plant   285 DHYLGKELVENLSVLRFSNLIFEPLWSRQYIRNVQFIFSEDFGTEGRGGYFDNYGIIRDIMQNHL 349

  Fly   269 LQILSLVAMEKPVSCHPDDIRDEKVKVLKSIEALTLDDMVLGQYLGNPQGTNDDARTGYVEDPTV 333
            ||||:|.|||.|||...:|||:||||||:|:..:.|:|:|:|||..:..|  ......|.:|.||
plant   350 LQILALFAMETPVSLDAEDIRNEKVKVLRSMRPIKLEDVVIGQYKSHSIG--GVTYPSYTDDKTV 412

  Fly   334 SNDSNTPTYALGVLKINNERWQGVPFILRCGKALNERKAEVRIQYQDVPGDIFEGN--TKR---- 392
            ...|.|||:|...|.|:|.||.||||:::.|||||.|.||:|:|::.|||:::..|  |.|
plant   413 PKGSLTPTFAAAALFIDNARWDGVPFLMKAGKALNTRSAEIRVQFRHVPGNLYNRNSGTDRDQTT 477

  Fly   393 NELVIRVQPGEALYFKMMTKSPGITFDIEETELDLTYEHRYKDSYLPDAYERLILDVFCGSQMHF 457
            |||||||||.||:|.|:..|.||:...::::.|:|.|..||... :|||||||:||...|.:..|
plant   478 NELVIRVQPDEAIYLKINNKVPGLGMRLDQSNLNLLYSARYSKE-IPDAYERLLLDAIEGERRLF 541

  Fly   458 VRSDELREAWRIFTPILHQIEKEHIRPITYQYGSRGP 494
            :|||||..||.:|||:|.:||::...|..|.||||||
plant   542 IRSDELDAAWALFTPLLKEIEEKKTTPEFYPYGSRGP 578

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zw	NP_523411.1	zwf	35..498	CDD:273312	222/470 (47%)
		G6PD_N	39..213	CDD:278882	74/177 (42%)
		G6PD_C	216..508	CDD:280876	145/285 (51%)
G6PD3	NP_173838.1	PLN02333	1..599	CDD:215191	228/492 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	149	1.000	Domainoid score	I1422
eggNOG	1	0.900	-	-		E1_COG0364
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62474
OrthoDB	1	1.010	-	-		D383995at2759
OrthoFinder	1	1.000	-	-		FOG0001006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100726
Panther	1	1.100	-	-	O	PTHR23429
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X665
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.830