DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Zw and G6PD5

DIOPT Version :9

Sequence 1:	NP_523411.1	Gene:	Zw / 32974	FlyBaseID:	FBgn0004057	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001325679.1	Gene:	G6PD5 / 822349	AraportID:	AT3G27300	Length:	587	Species:	Arabidopsis thaliana

Alignment Length:	491	Identity:	246/491 - (50%)
Similarity:	344/491 - (70%)	Gaps:	25/491 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 TFVIFGASGDLAKKKIYPTLWWLYRDDLL-PKPTKFCGYARSMLTVDSIKEQCLPYMKVQPHEQK 100
            :.::.||||||||||.:|.|:.|:....| |......|||||.:|.:.::::...|:..:.:..|
plant   104 SIIVLGASGDLAKKKTFPALFNLFHQGFLNPDEVHIFGYARSKITDEELRDKIRGYLVDEKNASK 168

  Fly   101 KYE---EFWALNEYVSGRYDGRTGFELLNQQL---EIMEN--KNKANRIFYLALPPSVFEEVTVN 157
            |.|   :|..|.:||||.||...||:.|::.:   ||.:.  :..:.|:|||||||||:..|:..
plant   169 KTEALSKFLKLIKYVSGPYDSEEGFKRLDKAILEHEISKKTAEGSSRRLFYLALPPSVYPPVSKM 233

  Fly   158 IKQICMS---VCGWNRVIIEKPFGRDDASSQALSDHLAGLFQEDQLYRIDHYLGKEMVQNLMTIR 219
            ||..|.:   :.||.|:::|||||:|..|::.||..:..||:|.|:||||||||||:|||::.:|
plant   234 IKAWCTNKSDLGGWTRIVVEKPFGKDLESAEQLSSQIGALFEEPQIYRIDHYLGKELVQNMLVLR 298

  Fly   220 FGNKILSSTWNRENIASVLITFKEPFGTQGRGGYFDEFGIIRDVMQNHLLQILSLVAMEKPVSCH 284
            |.|::....|||:|||:|.|.|:|.|||:||||||||:|||||::||||||:|.|||||||:|..
plant   299 FANRLFLPLWNRDNIANVQIVFREDFGTEGRGGYFDEYGIIRDIIQNHLLQVLCLVAMEKPISLK 363

  Fly   285 PDDIRDEKVKVLKSIEALTLDDMVLGQYLGNPQGTNDDARTGYVEDPTVSNDSNTPTYALGVLKI 349
            |:.|||||||||:|:..:..:::|||||            .||.:||||.|||||||:|..:|:|
plant   364 PEHIRDEKVKVLQSVIPIKDEEVVLGQY------------EGYRDDPTVPNDSNTPTFATTILRI 416

  Fly   350 NNERWQGVPFILRCGKALNERKAEVRIQYQDVPGDIFE-GNTKRNELVIRVQPGEALYFKMMTKS 413
            |||||:||||||:.|||::.:||::|||::|||||||: .|..|||.|||:||.||:|.|:..|.
plant   417 NNERWEGVPFILKAGKAMSSKKADIRIQFKDVPGDIFKCQNQGRNEFVIRLQPSEAMYMKLTVKQ 481

  Fly   414 PGITFDIEETELDLTYEHRYKDSYLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPILHQIE 478
            ||:.....::||||:|:.||:|..:|:||||||||...|.|.||||.|||:.||.||||:||:|:
plant   482 PGLEMQTVQSELDLSYKQRYQDVSIPEAYERLILDTIRGDQQHFVRRDELKAAWEIFTPLLHRID 546

  Fly   479 KEHIRPITYQYGSRGPKEADRKCEENNFKYSGSYKW 514
            |..::.:.|:.|||||.|||:..::..:..:..|.|
plant   547 KGEVKSVPYKQGSRGPAEADQLLKKAGYMQTHGYIW 582

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zw	NP_523411.1	zwf	35..498	CDD:273312	242/473 (51%)
		G6PD_N	39..213	CDD:278882	78/185 (42%)
		G6PD_C	216..508	CDD:280876	163/292 (56%)
G6PD5	NP_001325679.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	344	1.000	Domainoid score	I234
eggNOG	1	0.900	-	-		E1_COG0364
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37906
Inparanoid	1	1.050	492	1.000	Inparanoid score	I326
OMA	1	1.010	-	-		QHG62474
OrthoDB	1	1.010	-	-		D383995at2759
OrthoFinder	1	1.000	-	-		FOG0001006
OrthoInspector	1	1.000	-	-		otm2885
orthoMCL	1	0.900	-	-		OOG6_100726
Panther	1	1.100	-	-	O	PTHR23429
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X665
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840