DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zw and SPCC794.01c

DIOPT Version :9

Sequence 1:	NP_523411.1	Gene:	Zw / 32974	FlyBaseID:	FBgn0004057	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001342729.1	Gene:	SPCC794.01c / 2539576	PomBaseID:	SPCC794.01c	Length:	475	Species:	Schizosaccharomyces pombe

Alignment Length:	464	Identity:	168/464 - (36%)
Similarity:	252/464 - (54%)	Gaps:	12/464 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 TFVIFGASGDLAKKKIYPTLWWLYRDDLLPKPTKFCGYARSMLTVDSIKEQCLPYMKVQP---HE 98
            :.::||||||||.|..:|.|:.||...::|:..:..|||||.|:.::..:....::.:..   ..
pombe     3 SIIVFGASGDLATKMTFPALFALYVRKIIPEDFQIIGYARSKLSQEAANKIVTAHIPIDDTVGAS 67

  Fly    99 QKKYEEFWALNEYVSGRYDGRTGFELLNQQLEIMEN--KNKANRIFYLALPPSVFEEVTVNIKQI 161
            ||....|....:||.|.||....||:||..:...|.  .::..|||||.|||.:|..|:..||..
pombe    68 QKALNTFVEHYKYVPGTYDKPESFEMLNSIIAEKETAPASECTRIFYLVLPPHLFAPVSELIKSK 132

  Fly   162 CMSVCGWNRVIIEKPFGRDDASSQALSDHLAGLFQEDQLYRIDHYLGKEMVQNLMTIRFGNKILS 226
            ........|:|:|||.|.|..|:.|:...|:..:.....:::||:||::|:.....|||.|.:..
pombe   133 AHPNGMVTRLIVEKPIGFDYKSADAILSDLSKHWSAKDTFKVDHFLGEDMIDGFTAIRFANSMFE 197

  Fly   227 STWNRENIASVLITFKEPFGTQGRGGYFDEFGIIRDVMQNHLLQILSLVAMEKPVSCHPDDIRDE 291
            ..||||:|.||.:.|:|.||.:||||||:..||:|||:||||||:|:|:.:|:|.|...:||...
pombe   198 PIWNREHIESVRVDFREDFGCEGRGGYFEGAGILRDVVQNHLLQLLTLLCIEEPKSQDAEDIIKC 262

  Fly   292 KVKVLKSIEALTLDDMVLGQYLGNPQGTNDDARTGYVEDPTVSNDSNTPTYALGVLKINNERWQG 356
            ||..|||:..::.:|:|.|||..:..|    ...||.|...|::||...|:....|:....||:|
pombe   263 KVDFLKSLHPVSKEDIVYGQYTKSANG----KVPGYRELDGVADDSEVSTFCALQLRSEAPRWKG 323

  Fly   357 VPFILRCGKALNERKAEVRIQYQDVPGDIFEGNTKRNELVIRVQPGEALYFKMMTKSPGITFDIE 421
            :|.|:..||.|:....|.||.::...|.:|......|.||:||.|.|.:..|...|.||.:..|.
pombe   324 IPIIISAGKGLDRDYFEARITFKRREGGMFPTVDSSNVLVLRVYPKEFIALKGHIKQPGFSRQIV 388

  Fly   422 ETELDLTYEHRYKDSYLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPILHQIEKEHIRPIT 486
            ...||:.|...:.|:::..|||.:|.|...|...||:..||:|.:|:||..:|.  ....:.|:.
pombe   389 PVTLDVKYPEAFPDTWIHKAYEVVIADAINGKHTHFISDDEVRTSWKIFDDVLD--TTGDLSPLP 451

  Fly   487 YQYGS-RGP 494
            |.:|| .||
pombe   452 YAFGSHHGP 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zw	NP_523411.1	zwf	35..498	CDD:273312	168/464 (36%)
		G6PD_N	39..213	CDD:278882	60/178 (34%)
		G6PD_C	216..508	CDD:280876	108/280 (39%)
SPCC794.01c	NP_001342729.1	Zwf	1..475	CDD:223441	168/464 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0364
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62474
OrthoFinder	1	1.000	-	-		FOG0001006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23429
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X665
TreeFam	1	0.960	-	-
	7	6.880