Protein Alignment Ranbp21 and XPO1A

DIOPT Version :10

• Sequence 1: NP_608339.2
• Gene: Ranbp21 / 32970
• FlyBaseID: FBgn0031051
• Length: 1241
• Species: Drosophila melanogaster
• Sequence 2: NP_197204.1
• Gene: XPO1A / 831565
• AraportID: AT5G17020
• Length: 1075
• Species: Arabidopsis thaliana
• Alignment Length: 1302
• Identity: 239/1302 - (18%)
• Similarity: 421/1302 - (32%)
• Gaps: 469/1302 - (36%)

  Fly    42 KEESPMCAQVGLFLASSPQSNQQVRH------------FGLQLIEYTIKYRWNCITHEE----KV 90
            |||.....|:...|.::|....||.|            |.||::|..||||||.:..|:    |.
plant    31 KEERAAADQILRDLQANPDMWLQVVHILQNTNSLDTKFFALQVLEGVIKYRWNALPVEQRDGMKN 95

  Fly    91 YIKDNAIKMLNVGVGPAEDRSLLPTKDALSRIIVEMIKREWPQQWSDLLPELSQACTKGEAQTEL 155
            ||.:..:::.:   ..|..||.....:.|:.|:|:::|.:||.:|:..:|:|..|....|...|.
plant    96 YISEVIVQLSS---NEASFRSERLYVNKLNVILVQIVKHDWPAKWTSFIPDLVAAAKTSETICEN 157

  Fly   156 VLLVFLRLVEDVALLQTIESNQRR-KDMYQALNNNMNDIFEFFLRLVEQHVTAFRETTRLCNYT- 218
            .:.:...|.|:|......|..|:: |::.|:||:....|.|                  ||.|.
plant   158 CMAILKLLSEEVFDFSRGEMTQQKIKELKQSLNSEFKLIHE------------------LCLYVL 204

  Fly   219 KANAHSRVVEMVLLTLSGFVEWVSIQHIMSSNGKLMHFLCILLNDKAFQCNAAECLAQITNRKGQ 283
            .|:....::...|..|..::.|:
plant   205 SASQRQDLIRATLSALHAYLSWI------------------------------------------ 227

  Fly   284 TKERKPLLQLFNEEPLRYIYQASQIPADTSSTLAVEQHLNFLKKLLQVLNGMAQQLVALWGKDDA 348
                          ||.||::         |||     |..|.|...|
plant   228 --------------PLGYIFE---------STL-----LETLLKFFPV----------------- 247

  Fly   349 TQRPVHLEVLLECLLLLVQHPSLGLSHGSALIWQLLLKHEPSSKDFAMVNYIPKL------IHTI 407
               |.:..:.::||..:.     .|:.|                ||..|.|:...      :..|
plant   248 ---PAYRNLTIQCLTEVA-----ALNFG----------------DFYNVQYVKMYTIFIGQLRII 288

  Fly   408 APRIVKLPYPASASSPASLSTEAYIRLEHDSEEEYALYFFRCRTDFLEIFRLATL-----VQPLV 467
            .|...|:|   .|.|..|...:|:|       :..||:|    |.|.: |.:..|     |..|:
plant   289 LPPSTKIP---EAYSSGSGEEQAFI-------QNLALFF----TSFFK-FHIRVLESTPEVVSLL 338

  Fly   468 TYGYCEQWLQQRLRNAQIEADAEVKSGNVSCSVLDPVYLE-WDALVSVLDGVLSRILLVAERPSV 531
            ..|.      :.|.|.....|.||..          |.|: |::||..|......    ::.|:|
plant   339 LAGL------EYLINISYVDDTEVFK----------VCLDYWNSLVLELFDAHHN----SDNPAV 383

  Fly   532 PAGLRLLEECLKLETINPLTYSILLSCISALFVFLSMSACQITATNCVAMSGVSLLPRVLDKIFR 596
            .|.|..|:                                             ..||.::|.:
plant   384 SASLMGLQ---------------------------------------------PFLPGMVDGL-- 401

  Fly   597 ALVMKPPNELEKVQAKSAKNLRRHAAS-----LLVKLAHKYPLLLLPVFEQINGHVELLLKEPGK 656
                       ..|....:.|..|..|     ::.::|....:|::   |..||::   ::|..|
plant   402 -----------GSQVMQRRQLYSHPMSKLRGLMINRMAKPEEVLIV---EDENGNI---VRETMK 449

  Fly   657 HQLCRLMRTTLQEALILISN-HFCDFERQTLFIEHIVQDKRTEWLAFGDALKSPLDFMSFVGLDK 720
            .....:....::|.||.:|: ...|.|:|.|       .|..:.|:..:...:.|:.:.:.
plant   450 DNDVLVQYKIMRETLIYLSHLDHDDTEKQML-------RKLNKQLSGEEWAWNNLNTLCWA---- 503

  Fly   721 PPIFAVEGAVTLQNRSRLLDALHVVLGVVKRCTWPDDPER----AQRGGFVIGCTELGNPICRNP 781
              |.::.|::.....:|.|  :.|:..::..|......:.    |....:|:|         :.|
plant   504 --IGSISGSMAEDQENRFL--VMVIRDLLNLCEITKGKDNKAVIASNIMYVVG---------QYP 555

  Fly   782 ATKHIVPLLSHVLSLMRVLNELFAPEALQALSEGYRGIHGMMEHEKKLLMGICALPTDPLDTTIR 846
            ..     |.:|...|..|:|:||     :.:.|.:.|:..|          .|       ||.::
plant   556 RF-----LRAHWKFLKTVVNKLF-----EFMHETHPGVQDM----------AC-------DTFLK 593

  Fly   847 SEPTAFEKMQTFMMMVTEGCYHLMGSAGPSLGRDLYQLMGLSDAIVTNVFSRMDLVPDYRLRPII 911
                ..:|.:...::|.      :|...|.:..   .|.||:..:       .||.| :::.
plant   594 ----IVQKCKRKFVIVQ------VGENEPFVSE---LLTGLATTV-------QDLEP-HQIH--- 634

  Fly   912 RVFFKPFVYSCPPSFYDSVLVPLFAHLAPLMCERLTRRWIYIASLYESGQLDGEVNDTQEVLEDQ 976
                         |||:||...:.|...|...:...:|.:.:.: .:..::.|:...:.|.|:||
plant   635 -------------SFYESVGNMIQAESDPQKRDEYLQRLMALPN-QKWAEIIGQARHSVEFLKDQ 685

  Fly   977 ------LNRTLTRE-----------------YLDVLKIALVGGQIGADHVAAG---ANANS---- 1011
                  ||...|..                 :||:|.:..:..::.:.::..|   |:..|
plant   686 VVIRTVLNILQTNTSAATSLGTYFLSQISLIFLDMLNVYRMYSELVSTNITEGGPYASKTSFVKL 750

  Fly  1012 -NSVAMEN---EEHSMDSAPQSRAIQSALLSDIISDLGGKLLRN--------------GLIGNY- 1057
             .||..|.   .|..:|.|.....|....:..::..:.|...||              .:|..|
plant   751 LRSVKRETLKLIETFLDKAEDQPHIGKQFVPPMMESVLGDYARNVPDARESEVLSLFATIINKYK 815

  Fly  1058 ----------------------------------VLMTLLKAIAWNDGMCSMKAVNIAAPVMRFL 1088
                                              ...:||:|||   ..|....:.:::|.::.:
plant   816 ATMLDDVPHIFEAVFQCTLEMITKNFEDYPEHRLKFFSLLRAIA---TFCFPALIKLSSPQLKLV 877

  Fly  1089 A-----AEKLMDENKAVTAFTAVLQGMQVHGQHE-ANQ---SGLVTLGVQFYELL-----RPQFP 1139
            .     |.:..:.|.|.|....:|:.::...|.| .||   |..:.:..:.:.:|     :|.|.
plant   878 MDSIIWAFRHTERNIAETGLNLLLEMLKNFQQSEFCNQFYRSYFMQIEQEIFAVLTDTFHKPGFK 942

  Fly  1140 ILSEVLQH---IPSVNAADIQKFDEKIAVAPVKGNKVDRAKKDI------FKKLTAQLVGRSVNQ 1195
            :...|||.   :|...|.....:|......|...|.....:..|      |..:||..|.:.||.
plant   943 LHVLVLQQLFCLPESGALTEPLWDATTVPYPYPDNVAFVREYTIKLLSSSFPNMTAAEVTQFVNG 1007

  Fly  1196 LF 1197
            |:
plant  1008 LY 1009

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ranbp21	NP_608339.2	IBN_N	34..101	CDD:397745	23/74 (31%)
		Xpo1	116..274	CDD:462459	30/159 (19%)
		Exportin-5	319..1196	CDD:437105	175/1004 (17%)
XPO1A	NP_197204.1	CRM1	4..1044	CDD:227432	239/1302 (18%)