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Protein Alignment Ranbp21 and Xpo5

DIOPT Version :10

Sequence 1:	NP_608339.2	Gene:	Ranbp21 / 32970	FlyBaseID:	FBgn0031051	Length:	1241	Species:	Drosophila melanogaster
Sequence 2:	NP_082474.1	Gene:	Xpo5 / 72322	MGIID:	1913789	Length:	1204	Species:	Mus musculus

Alignment Length:	1258	Identity:	435/1258 - (34%)
Similarity:	698/1258 - (55%)	Gaps:	88/1258 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 ALAAELASAIDLVMNPMTQQQARLEAYMACERFKEESPMCAQVGLFLASSPQSNQQVRHFGLQLI 73
            ||..||..|:.::|:|.:.|:.||||...||.|||:.|:|...||.||...|. ..|||||||::
Mouse     8 ALCEELVKAVTVMMDPSSTQRYRLEALKFCEEFKEKCPICVPCGLKLAEKTQI-AIVRHFGLQIL 71

  Fly    74 EYTIKYRWNCITHEEKVYIKDNAIKML-NVGVGPAEDRSLLPTKDALSRIIVEMIKREWPQQWSD 137
            |:.:|:|||.::..||||:|::.:::: |..:...|:.:.:  ||.||||:||||||||||.|.|
Mouse    72 EHVVKFRWNSMSRLEKVYLKNSVMELIANGTLRILEEENHI--KDVLSRIVVEMIKREWPQHWPD 134

  Fly   138 LLPELSQACTKGEAQTELVLLVFLRLVEDVALLQTIESNQRRKDMYQALNNNMNDIFEFFLRLVE 202
            :|.||.....:||.|.|||:.:.|||.|||...||:.: |||:|:.|.|..||..|..|.|..::
Mouse   135 MLMELDTLFRQGETQRELVMFILLRLAEDVVTFQTLPT-QRRRDIQQTLTQNMERILNFLLNTLQ 198

  Fly   203 QHVTAFRE-TTRLCNYTKANAHSRVVEMVLLTLSGFVEWVSIQHIMSSNGKLMHFLCILLNDKAF 266
            ::|..::: .|......:|.|:.||....|.||:|:::|||:.||.:.|.||:..||:|||::..
Mouse   199 ENVNKYQQMKTDSSQEAEAQANCRVSVAALNTLAGYIDWVSLNHITAENCKLVETLCLLLNEQEL 263

  Fly   267 QCNAAECLAQITNRKGQTKERKPLLQLFNEEPLRYIYQASQIPADTSSTLAVEQHLNFLKKLLQV 331
            |..|||||....:|||:.::||.|:.||.:..:.||..|:| .||...  .||:|..|||:|.||
Mouse   264 QLGAAECLLIAVSRKGKLEDRKRLMILFGDVAMHYILSAAQ-TADGGG--LVEKHYLFLKRLCQV 325

  Fly   332 LNGMAQQLVALWGKDDATQRPVHLEVLLECLLLLVQHPSLGLSHGSALIWQLLLKHEPSSKDFAM 396
            |..:...|.||...|...|.|::..:.||..|....|||..|...:.:.|..|.:||..|:|.|:
Mouse   326 LCALGNLLCALLALDANIQTPINFGMYLESFLAFTTHPSQFLRSSTHMTWGALFRHEVLSRDPAL 390

  Fly   397 VNYIPKLIHTIAPRIVKLPYPASASSPASLSTEAYIRLEHDSEEEYALYFFRCRTDFLEIFRLAT 461
            :..|||.:......:||:.:|:...||:.    .|.|.:.||:|::..:|...|....|:.|...
Mouse   391 LAVIPKYLRASMTNLVKMGFPSKTDSPSC----EYSRFDFDSDEDFNAFFNSSRAQHGEVVRCVC 451

  Fly   462 LVQPLVTYGYCEQWLQQRLRNAQIEADAEVKSGNVS------------CSVLDPVYLEWDALVSV 514
            .:.|..::....:||:.:|       .|.:.:|.|:            ||:..|.|::|:|:...
Mouse   452 RLDPKTSFQMAAEWLKYQL-------SASIDTGPVNSCSTAGTGEGGFCSIFSPSYVQWEAMTFF 509

  Fly   515 LDGVLSRILLVAERPSVPA--GLRLLEECLKLETINPLTYSILLSCISALFVFLSMSACQITATN 577
            |:.|::::....::..:|.  |:.||:..|..|..:||..|.:|:.:||||.|::...
Mouse   510 LESVINQMFRTLDKEELPVSDGIELLQLVLNFEIKDPLVLSCVLTNVSALFPFVTYKP------- 567

  Fly   578 CVAMSGVSLLPRVLDKIFRALVMKPPNELEKVQAKSAKNLRRHAASLLVKLAHKYPLLLLPVFEQ 642
                   :.||:|..|:|..:..:...|.:..:.::.:|:||||.|.:.|:...||.|:||.|:.
Mouse   568 -------AFLPQVFSKLFSFVTFESVGESKAPRTRAVRNVRRHACSSINKMCRDYPDLVLPNFDM 625

  Fly   643 INGHVELLLKEPGKHQLCRLMRTTLQEALILISNHFCDFERQTLFIEHIVQDKRTEWLA--FGDA 705
            :..||:.||.  .:..|.::.:..|.|||:|:||.|.|:|||.||:|.::......||:  ...|
Mouse   626 LYSHVKQLLS--NELLLTQMEKCALMEALVLVSNQFKDYERQKLFLEELMAPVVNIWLSEEMCRA 688

  Fly   706 LKSPLDFMSFVGLD-KPPIFAVEGAVTLQNRSRLLDALHVVLGVVKRCTWPDDPERAQRGGFVIG 769
            |.....|:::||.| |....|||....| ||:|:...::.:|||::|.:||.|.|.|:.||||:|
Mouse   689 LSDIDSFIAYVGADLKSCDPAVEDPCGL-NRARMSFCVYSILGVMRRTSWPSDLEEAKAGGFVVG 752

  Fly   770 CTELGNPICRNPATKHIVPLLSHVLSLMRVLNELFAPEALQALSEGYRGIHGMMEHEKKLLMGIC 834
            .|..||||.|||.|:.|:.||.::|:|:|..|.|:.||.|..::|.:.....::|.||..::|
Mouse   753 YTPSGNPIFRNPCTEQILRLLDNLLALVRTHNTLYTPEMLTKMAEPFTKALDIVESEKTAILG-- 815

  Fly   835 ALPTDPLDTTIRSEP---TAFEKMQTFMMMVTEGCYHLMGSAGPSLGRDLYQLMGLSDAIVTNVF 896
             ||...|:  ....|   |..|:||.|..::.|.|||::|.||||:.:|.|.:..|:..::.:.|
Mouse   816 -LPQPLLE--FNDHPVYRTTLERMQRFFGILYENCYHILGKAGPSMQQDFYTVEDLASQLLGSAF 877

  Fly   897 SRMDLVPDYRLRPIIRVFFKPFVYSCPPSFYDSVLVPLFAHLAPLMCERLTRRWIYI---ASLYE 958
            ..::.:||:|||.::|||.||.|..||...|::::.|:...|...:..||:::|..|   :.|..
Mouse   878 VNLNNIPDFRLRSMLRVFVKPLVLFCPSEHYETLISPILGPLFTYLHMRLSQKWHVINQRSILCG 942

  Fly   959 SGQLDGEVNDTQEVLEDQLNRTLTREYLDVLKIALVGGQIGADHVAAGANANSNSVAMENEEHSM 1023
            ..::..:..::||:||:||.|.||||.:|::....|..:. |||.||......:...|..|
Mouse   943 EDEIAEDNPESQEMLEEQLVRMLTREAMDLIMACCVSKKT-ADHTAAPTADGDDEEMMATE---- 1002

  Fly  1024 DSAPQSRAIQSALLSDIISDLGGKLLRNGLIGNYVLMTLLKAIAWNDGM-CSMKAVNIAAPVMRF 1087
             .||.| .::       ::|||..|:::..:...:|:|...::.|.|.: |......:..|:::.
Mouse  1003 -VAPSS-VVE-------LTDLGKCLMKHEDVCTALLITAFNSLTWKDTLSCQRATTQLCWPLLKQ 1058

  Fly  1088 LAAEKLMDENKAVT-AFTAVLQGMQVHGQHEANQSGLVTLGVQFYELLRPQFPILSEVLQHIPSV 1151
            :.:..|:.:  ||| .||:||:|:|:||||:...:.||.|..|.||.|||::..:..|::.||.:
Mouse  1059 VMSGTLLAD--AVTWLFTSVLKGLQMHGQHDGCMASLVHLAFQIYEALRPRYLEIRAVMEQIPEI 1121

  Fly  1152 NAADIQKFDEKIAVAPVKGNKVDRAKKDIFKKLTAQLVGRSVNQLFRHEVQIANLPPMQSHKAKG 1216
            |...:.:||.|: :.|......|:.:||.||:|.|..:|:.:.:.||.||.|.|||.: ..|.|.
Mouse  1122 NKESLDQFDCKL-LNPSLQKAADKRRKDHFKRLIAGCIGKPLGEQFRKEVHIKNLPWL-FKKPKP 1184

  Fly  1217 SMGTTADIMDSNQNASLARLFGP 1239
            .:.|  :::|| :...||.:|.|
Mouse  1185 MLET--EVLDS-EEGGLATIFEP 1204

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.