Protein Alignment Ranbp21 and xpo5

DIOPT Version :9

• Sequence 1: NP_001285453.1
• Gene: Ranbp21 / 32970
• FlyBaseID: FBgn0031051
• Length: 1241
• Species: Drosophila melanogaster
• Sequence 2: XP_031757462.1
• Gene: xpo5 / 394717
• XenbaseID: XB-GENE-5947328
• Length: 1245
• Species: Xenopus tropicalis
• Alignment Length: 1254
• Identity: 412/1254 - (32%)
• Similarity: 682/1254 - (54%)
• Gaps: 76/1254 - (6%)

  Fly     9 ALAAELASAIDLVMNPMTQQQARLEAYMACERFKEESPMCAQVGLFLASSPQSNQQVRHFGLQLI 73
            ||..:|..|:.:::.|.::|:.||||...||.|||.||:|...||.|::...| ..||||||.::
 Frog    45 ALCEQLVRAVTVMLEPESRQEYRLEALKFCEEFKERSPLCVPCGLQLSNRSHS-PCVRHFGLHVL 108

  Fly    74 EYTIKYRWNCITHEEKVYIKDNAIKMLNVGVGP-AEDRSLLPTKDALSRIIVEMIKREWPQQWSD 137
            |:.||:|||.::.||||.:||:.:.:::.|:.| .|:.|.:  ||.::||:|||.||||||.|.|
 Frog   109 EHVIKFRWNDMSREEKVCLKDSVMDLISHGMHPILEEESHI--KDMMARIVVEMAKREWPQHWPD 171

  Fly   138 LLPELSQACTKGEAQTELVLLVFLRLVEDVALLQTIESNQRRKDMYQALNNNMNDIFEFFLRLVE 202
            ||.||......||||||||:.:.|||.|||...|.:.: |||:|:...:...|:.:|.|.|.:::
 Frog   172 LLNELDSLTRVGEAQTELVMFILLRLAEDVVTFQNLPT-QRRRDIQTTMTQKMDVLFAFMLNILQ 235

  Fly   203 QHVTAFRE-TTRLCNYTKANAHSRVVEMVLLTLSGFVEWVSIQHIMSSNGKLMHFLCILLNDKAF 266
            |.|..::. .|...|..||....||....|.||:|:::||:|.|||:.|.||:..||:||::...
 Frog   236 QSVQQYQHLKTDPANSVKAQGMCRVAVASLKTLAGYIDWVAITHIMADNCKLLGMLCVLLSEPEL 300

  Fly   267 QCNAAECLAQITNRKGQTKERKPLLQLFNEEPLRYIYQASQIPADTSSTLAVEQHLNFLKKLLQV 331
            |..|||||....:|||:.::|.|||.||.:|.:.||...:|: ||| .||..:::: .||::.|:
 Frog   301 QLEAAECLLIAVSRKGKLEDRIPLLILFGDEAIEYILSVAQM-ADT-ETLEEKRYI-LLKRICQL 362

  Fly   332 LNGMAQQLVALWGKDD-ATQRPVHLEVLLECLLLLVQHPSLGLSHGSALIWQLLLKHEPSSKDFA 395
            :..:..|:.||....| ....|.:....||.||...:|.|..|:..:.|.|..:.:||..|:...
 Frog   363 ICTLGTQICALTQSPDLKVNVPGNFNKYLETLLSFTRHASQFLTSSTILTWGTIFRHEVLSRHPQ 427

  Fly   396 MVNYIPKLIHTIAPRIVKLPYPASASSPASLSTEAYIRLEHDSEEEYALYFFRCRTDFLEIFRLA 460
            ::..||..:.:....||::.:|:..:||:.    .|.|::::|:|::..:|...|.....:.|.|
 Frog   428 LLAAIPDFLRSSMVSIVRVGFPSKDNSPSC----KYSRMDYESDEDFNGFFNSFRALMGGVVRAA 488

  Fly   461 TLVQPLVTYGYCEQWLQQRLRNAQIEADAEVKSGNVSCSVLDPVYLEWDALVSVLDGVLSRILLV 525
            ..:.|...:...::|||.:|...........:.|:..||.....:|:|:|:....:.|.|::..|
 Frog   489 CYLDPHTGFCIAKEWLQFQLSAPLDPGPHNAQPGDALCSPTSTSFLQWEAMTFFCECVTSQLFRV 553

  Fly   526 AERPSVPA--GLRLLEECLKLETINPLTYSILLSCISALFVFLSMSACQITATNCVAMSGVSLLP 588
            ..:..:|.  |:.||::.|..||::||..|.:|:.:|:|..|::          |::    |.:|
 Frog   554 VPKEELPVAEGIGLLQQVLSYETMDPLILSFVLTNLSSLMPFIT----------CLS----SYVP 604

  Fly   589 RVLDKIFRALVMKPPNELEKVQAKSAKNLRRHAASLLVKLAHKYPLLLLPVFEQINGHVELLLKE 653
            .||.|:..|:......:::..:::...|:||||.|.|:|:...||.|:.|.|||::..|..||
 Frog   605 PVLSKLLDAISFPLSGDMKVSKSRGEMNVRRHANSSLIKVCRDYPELVQPHFEQLHARVTALL-- 667

  Fly   654 PGKHQLCRLM-RTTLQEALILISNHFCDFERQTLFIEHIV-------QDKRTEWLAFGDALKSPL 710
             |:.||...| :..|.|||||.||.|..::||.:.:|.::       ..::|:     .|...|.
 Frog   668 -GEEQLLTQMGKCALMEALILASNQFKSYDRQQVLLEELIGPLVSGCVSEKTQ-----RAFSGPD 726

  Fly   711 DFMSFVGLDKPPIFAVEGAVTLQNRSRLLDALHVVLGVVKRCTWPDDPERAQRGGFVIGCTELGN 775
            :|:.|||.|.......|......:||:|......:||:|||..||.|||.|:.||||||.:..|.
 Frog   727 EFIYFVGADILMHQQEEEDRGAPSRSQLSLCTFALLGMVKRSQWPTDPEEAKAGGFVIGYSASGA 791

  Fly   776 PICRNPATKHIVPLLSHVLSLMRVLNELFAPEALQALSEGYRGIHGMMEHEKKLLMGI------- 833
            |:.|||..:.::.:|..:|:|:|.:|.|:.||.:..:.:.:.....|:..::|||||.
 Frog   792 PLLRNPGARLLLKVLDSLLALIRTMNNLYLPEVMGKMGDTFCKSLNMLAMDRKLLMGTSQSAIED 856

  Fly   834 CALPTDPLDTTIRSEPTAFEKMQTFMMMVTEGCYHLMGSAGPSLGRDLYQLMGLSDAIVTNVFSR 898
            |.||.          .|...::|.|...:.:.|..::|..|||:..:.|.:..|:..::::||:.
 Frog   857 CDLPA----------KTNLSRIQFFFASLFDNCCQILGHCGPSMPHEFYSVPDLASRLLSSVFTN 911

  Fly   899 MDLVPDYRLRPIIRVFFKPFVYSCPPSFYDSVLVPLFAHLAPLMCERLTRRWIYI--ASLYESGQ 961
            .|.|||||||.|:||..||.:.|||...|:|::.|:...|...:.:||:::|:.|  .::.....
 Frog   912 ADNVPDYRLRLILRVLVKPLILSCPAEKYESLVCPILGPLIIYLYQRLSQKWLSINQRTVVSEED 976

  Fly   962 LDGEVNDTQEVLEDQLNRTLTREYLDVLKIALVGGQIGADHVAAGANANSNSVAMENEEHSMDSA 1026
            ...|.::.|||||:||.|.||||.:|::....:..: ..|..|:||:...::...:.:|..|.:
 Frog   977 YTEEDSECQEVLEEQLVRQLTREVVDLIGSCCIARK-SNDFCASGADVGHSAGQADGDEEEMMT- 1039

  Fly  1027 PQSRAIQSALLSDIISDLGGKLLRNGLIGNYVLMTLLKAIAWNDGM-CSMKAVNIAAPVMRFLAA 1090
              :.|:....:.  :::||..||.|..|...:|:.....:.|.|.| |...|.::..|:::.:.:
 Frog  1040 --TEAVAPGPIE--LTELGQFLLANEEISTSLLVISFSPLVWKDTMACQKAASHLCWPLLKQVMS 1100

  Fly  1091 EKLMDENKAVTAFTAVLQGMQVHGQHEANQSGLVTLGVQFYELLRPQFPILSEVLQHIPSVNAAD 1155
            ...:..:.|:..|:.:|.|:|.|||||:.:..||.|..|.||.||||:|.|..:::.:|.|....
 Frog  1101 ASPLPADAALCVFSNILCGLQTHGQHESCKFPLVQLSFQTYEALRPQYPELRGLMEQVPDVPRDS 1165

  Fly  1156 IQKFDEKIAVAPVKGNKVDRAKKDIFKKLTAQLVGRSVNQLFRHEVQIANLPPMQSHKAKGSMGT 1220
            :::||.|:...|.|..  ::.:::.||||.|..:|:.:.:.||.||.|.|||.:...|.|.:  .
 Frog  1166 LEQFDAKLLAPPQKVG--EKKRREHFKKLIAGCIGKPLGEQFRKEVHIRNLPALFKKKTKSA--P 1226

  Fly  1221 TADIMDSNQNASLARLFGP 1239
            .:|.:.|:.::||..||.|
 Frog  1227 DSDSVLSSCDSSLVALFQP 1245

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ranbp21	NP_001285453.1	IBN_N	34..101	CDD:281761	31/66 (47%)
		Xpo1	116..274	CDD:285575	71/158 (45%)
xpo5	XP_031757462.1	CRM1	48..>383	CDD:227432	140/341 (41%)
		Xpo1	146..308	CDD:400614	72/164 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	442	1.000	Domainoid score	I536
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H69316
Inparanoid	1	1.050	655	1.000	Inparanoid score	I774
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D203278at2759
OrthoFinder	1	1.000	-	-		FOG0003520
OrthoInspector	1	1.000	-	-		otm48142
Panther	1	1.100	-	-	LDO	PTHR11223
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4056
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.160